سعر لوليب 300مجم 10قرص 2022

Gemfibrozil 300 mg tablets (Alfacure Pharmaceuticals, Egypt); fibrate lipid-regulating agent.

• Adjunct to diet for adults with very high serum triglycerides (Types IV and V hyperlipidemia) at risk of pancreatitisPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Reducing the risk of coronary heart disease in selected Type IIb patients without history of CHD who have not responded to diet and other measuresPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most frequent in the Helsinki Heart Study: gastrointestinal reactions, especially dyspepsia and abdominal pain; also acute appendicitis and atrial fibrillation more frequent than placebo.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Hepatic or severe renal dysfunction, including primary biliary cirrhosis.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Pre-existing gallbladder disease.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Hypersensitivity to gemfibrozil.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Combined use with an HMG-CoA reductase inhibitor increases the risk of myopathy, rhabdomyolysis and acute renal failure.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• May increase cholesterol excretion into bile and cause cholelithiasis; investigate if gallstones are suspected and discontinue if found.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• SimvastatinContraindicated combination (myopathy/rhabdomyolysis).DailyMed (U.S. National Library of Medicine)
• RosuvastatinAvoid; if unavoidable start rosuvastatin 5 mg and do not exceed 10 mg daily.DailyMed (U.S. National Library of Medicine)
• WarfarinUse caution; reduce warfarin dosage to maintain the desired prothrombin time and monitor frequently.DailyMed (U.S. National Library of Medicine)

• No adequate studies in pregnant women; use during pregnancy only if the potential benefit justifies the potential risk to the fetus.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Unknown whether excreted in human milk; because of tumorigenicity in animal studies, decide whether to discontinue nursing or the drug.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Gemfibrozil: Mechanism not definitely established; inhibits peripheral lipolysis, decreases hepatic extraction of free fatty acids and VLDL production, lowering triglycerides and raising HDL-C.