سعر فلوزاك 40 مجم 10 كبسولات 2022

Fluoxetine 40 mg hard gelatin capsules by Jedco int. co. for pharmaceuticals (Egypt); selective serotonin reuptake inhibitor antidepressant.

• Acute and maintenance treatment of major depressive disorder.Population: Adults and paediatric patients 8 years and olderDailyMed (U.S. National Library of Medicine)
• Acute and maintenance treatment of obsessions and compulsions in obsessive compulsive disorder.Population: Adults and paediatric patients 7 years and olderDailyMed (U.S. National Library of Medicine)
• Acute and maintenance treatment of binge-eating and vomiting behaviours in moderate to severe bulimia nervosa.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (≥5% and at least twice placebo): abnormal dreams, abnormal ejaculation, anorexia, anxiety, asthenia, diarrhoea, dry mouth, dyspepsia, flu syndrome, impotence, insomnia, decreased libido, nausea, nervousness, pharyngitis, rash, sinusitis, somnolence, sweating, tremor, vasodilatation and yawning.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Use with MAOIs intended to treat psychiatric disorders, or within 5 weeks of stopping fluoxetine, or starting fluoxetine within 14 days of stopping such an MAOI; starting fluoxetine in patients treated with linezolid or intravenous methylene blue.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant use with pimozide or thioridazine (QT prolongation).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: antidepressants increase the risk of suicidal thoughts and behaviours in children, adolescents and young adults; monitor closely for clinical worsening and emergence of suicidality.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Serotonin syndrome risk, increased with other serotonergic drugs (triptans, tricyclics, fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, St John's wort) and MAOIs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Increased risk of bleeding, especially with aspirin, NSAIDs, warfarin or other anticoagulants.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• MAOIs (including linezolid, intravenous methylene blue)Contraindicated: risk of serotonin syndrome.DailyMed (U.S. National Library of Medicine)
• Pimozide, thioridazineContraindicated: fluoxetine raises their levels via CYP2D6 inhibition and both prolong the QT interval.DailyMed (U.S. National Library of Medicine)
• Aspirin, NSAIDs, warfarinIncreased bleeding risk; monitor patients on warfarin when fluoxetine is started or stopped.DailyMed (U.S. National Library of Medicine)

• Published epidemiologic data and postmarketing reports have not established an increased risk of major birth defects or miscarriage; there are risks from untreated depression and of persistent pulmonary hypertension of the newborn and poor neonatal adaptation with SSRI exposure; exposure in the month before delivery is associated with a less than 2-fold increased risk of postpartum haemorrhage.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Fluoxetine and norfluoxetine are present in human milk; agitation, irritability, poor feeding and poor weight gain have been reported in exposed infants, who should be monitored.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Fluoxetine: The mechanism of action in depression and OCD is unknown but is presumed to be linked to inhibition of CNS neuronal uptake of serotonin (US PROZAC label).