سعر فلوكسامين 50 مجم 10 اقراص 2022

Fluvoxamine maleate 50 mg tablets, pack of 10, by Pharo Pharma (Egypt); selective serotonin reuptake inhibitor.

• Treatment of obsessions and compulsions in obsessive compulsive disorder.Population: Adults and children/adolescents 8-17 yearsDailyMed (U.S. National Library of Medicine)

• Most common in adult OCD/depression trials (≥5% and at least twice placebo): nausea, somnolence, insomnia, asthenia, nervousness, dyspepsia, abnormal ejaculation, sweating, anorexia, tremor and vomiting.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Coadministration with tizanidine, thioridazine, alosetron or pimozide.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Use with MAOIs intended for psychiatric disorders or within 14 days of stopping either drug; starting fluvoxamine in patients on linezolid or intravenous methylene blue.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: antidepressants increase the risk of suicidal thinking and behaviour in children, adolescents and young adults; monitor closely.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Serotonin syndrome risk, increased with other serotonergic drugs and MAOIs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Gradual dose reduction is recommended when stopping.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Drugs metabolised by CYP1A2, CYP2C9, CYP3A4 or CYP2C19Fluvoxamine inhibits these isoenzymes and can raise levels of their substrates.DailyMed (U.S. National Library of Medicine)
• CarbamazepineElevated carbamazepine levels and toxicity reported.DailyMed (U.S. National Library of Medicine)
• Tricyclic antidepressantsPlasma TCA levels significantly increased.DailyMed (U.S. National Library of Medicine)

• SSRI exposure, particularly in the month before delivery, has been associated with a less than 2-fold increased risk of postpartum haemorrhage; see the full label for neonatal risks.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Fluvoxamine is present in human milk; most cases showed no adverse effects in the infant, but diarrhoea, vomiting, decreased sleep and agitation have been reported.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Fluvoxamine: Presumed to be linked to specific inhibition of serotonin reuptake in brain neurons (US fluvoxamine label).