سعر ايزوتريتينوين 20مجم 10 كبسولة جيلاتينية 2023

Oral isotretinoin 20 mg soft gelatin capsules (systemic retinoid) by Ranbaxy, used for severe acne.

• Severe recalcitrant nodular acne unresponsive to conventional therapy including systemic antibiotics, in non-pregnant patients aged 12 years and older.Population: Non-pregnant patients 12 years and olderDailyMed (U.S. National Library of Medicine)

• Reported reactions include dry mouth/lips (cheilitis), dry skin, hypertriglyceridaemia, raised liver enzymes (about 15% in trials), musculoskeletal pain, visual disturbances, gastrointestinal symptoms, and laboratory changes such as raised cholesterol and decreased HDL.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pregnancy (risk of life-threatening birth defects).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hypersensitivity to isotretinoin, vitamin A or any component.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: embryo-fetal toxicity; any exposure during pregnancy carries an extremely high risk of severe birth defects. Pregnancy must be excluded before, during and after treatment with effective contraception.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Psychiatric disorders (depression, psychosis, rarely suicidal ideation/behaviour, aggression): assess before and during treatment and stop if they occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Intracranial hypertension (pseudotumor cerebri), especially with tetracyclines; serious skin reactions (SJS/TEN); acute pancreatitis; lipid abnormalities; hearing impairment; hepatotoxicity; inflammatory bowel disease; musculoskeletal and ocular effects.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Vitamin AAvoid concomitant vitamin A supplements (additive retinoid adverse reactions).DailyMed (U.S. National Library of Medicine)
• TetracyclinesAvoid concomitant use: associated with intracranial hypertension (pseudotumor cerebri).DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnancy: increased risk of major congenital malformations, spontaneous abortion and premature birth; stop immediately if pregnancy occurs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Breastfeeding is not recommended during treatment and for at least 8 days after the last dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)

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