سعر ليسيتال 40مجم 30 قرص 2025

Citalopram 40 mg film-coated tablets, pack of 30, by Joswe Medical (Jordan) > Space Medical; selective serotonin reuptake inhibitor antidepressant.

• Major depressive disorder.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common adverse reaction (incidence at least 5% and twice placebo) is ejaculation disorder (primarily ejaculation delay); frequent adverse reactions in clinical trials included nausea (21%), dry mouth (20%), somnolence (18%), insomnia (15%) and increased sweating (11%).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Taking, or within 14 days of stopping, monoamine oxidase inhibitors (including linezolid or intravenous methylene blue).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Taking pimozide (risk of QT prolongation).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Known hypersensitivity to citalopram or any inactive ingredient (reactions have included angioedema and anaphylaxis).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased risk of suicidal thoughts and behaviours in pediatric and young adult patients taking antidepressants; monitor closely for clinical worsening and emergence of suicidal thoughts and behaviours.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Dose-dependent QT prolongation and Torsade de Pointes; avoid in congenital long QT syndrome, bradycardia, hypokalaemia or hypomagnesaemia, recent myocardial infarction or uncompensated heart failure; correct electrolytes and consider ECG monitoring.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Serotonin syndrome (especially with other serotonergic drugs), increased bleeding risk, activation of mania/hypomania, discontinuation syndrome, seizures, angle-closure glaucoma, hyponatraemia and sexual dysfunction.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Monoamine oxidase inhibitors (including linezolid, IV methylene blue)Contraindicated: risk of serotonin syndrome; allow 14 days between stopping one and starting the other.DailyMed (U.S. National Library of Medicine)
• PimozideContraindicated: risk of QT prolongation.DailyMed (U.S. National Library of Medicine)
• CYP2C19 inhibitorsIncrease citalopram exposure; maximum citalopram dose 20 mg/day.DailyMed (U.S. National Library of Medicine)

• Use of SSRIs late in pregnancy may increase the risk of persistent pulmonary hypertension of the newborn (PPHN); use in the month before delivery may increase the risk of postpartum haemorrhage; consider the risks of untreated depression.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Citalopram is present in human milk (relative infant dose about 0.7-9.4% of the weight-adjusted maternal dose); monitor breastfed infants for irritability, restlessness, excessive somnolence, decreased feeding and weight loss.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Citalopram: Presumed to be related to potentiation of central serotonergic activity through inhibition of neuronal serotonin (5-HT) reuptake; the exact mechanism is unclear (US label).