سعر ليفوكول 250 مجم 12 كبسولة 2022

Capsule containing chloramphenicol 250 mg, pack of 12 capsules, by El nasr (Egypt); amphenicol antibacterial.

• Bone marrow depression (reversible dose-related type and irreversible aplastic type), paroxysmal nocturnal haemoglobinuria; gastrointestinal reactions (nausea, vomiting, glossitis, stomatitis, diarrhoea, enterocolitis); neurotoxic reactions (headache, mild depression, confusion, delirium, optic and peripheral neuritis usually after long-term therapy).General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Contraindicated in patients with previous hypersensitivity and/or toxic reaction to chloramphenicol; must not be used for trivial infections (colds, influenza, throat infections) or as prophylaxis.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Boxed warning: serious and fatal blood dyscrasias (aplastic anaemia, hypoplastic anaemia, thrombocytopenia, granulocytopenia) occur after short-term and prolonged therapy; aplastic anaemia later terminating in leukaemia has been reported; use only when less dangerous agents will not be effective.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Gray syndrome toxicity in premature and full-term neonates and infants because of immature metabolism; excessive blood levels can result from recommended doses, so adjust the dose or measure blood concentrations.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Avoid repeated courses and treatment longer than needed; impaired liver or kidney function may cause excessive blood levels; overgrowth of nonsusceptible organisms including fungi may occur.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Other drugs that may cause bone marrow depressionConcurrent therapy should be avoided.DailyMed (U.S. National Library of Medicine)

• No adequate, well-controlled studies in pregnancy; orally administered chloramphenicol crosses the placenta; because of potential fetal toxicity (gray syndrome), give to a pregnant woman only if the potential benefit justifies the risk.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Excreted in human milk after oral administration; because of possible serious reactions in nursing infants, decide whether to discontinue nursing or the drug.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Baseline blood studies followed by periodic blood studies about every two days during therapy; discontinue on reticulocytopenia, leukopenia, thrombocytopenia, anaemia or other attributable findings (monitoring cannot exclude later irreversible marrow aplasia).General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Chloramphenicol: Chloramphenicol inhibits bacterial protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes; in vitro it is mainly bacteriostatic (US label).