سعر ليفوفلوكس 500مجم فيال وريد 2022

Vial for intravenous infusion containing levofloxacin 500 mg, pack of 1 vial, by Memphis (Egypt); fluoroquinolone antibacterial.

• Community-acquired pneumonia (500 mg every 24 h for 7-14 days).Population: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)
• Uncomplicated skin and skin structure infections (500 mg every 24 h for 7-10 days).Population: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)
• Chronic bacterial prostatitis (500 mg every 24 h for 28 days).Population: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (3% or more): nausea, headache, diarrhoea, insomnia, constipation and dizziness.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to levofloxacin or other quinolone antibacterials.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fluoroquinolones have been associated with disabling and potentially irreversible serious adverse reactions occurring together, including tendinitis and tendon rupture, peripheral neuropathy and CNS effects; discontinue immediately and avoid fluoroquinolones in patients who experience them. Fluoroquinolones may exacerbate muscle weakness in myasthenia gravis; avoid in patients with known history of myasthenia gravis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Boxed warning: because of these risks, reserve levofloxacin for patients with no alternative treatment options for uncomplicated urinary tract infection, acute bacterial exacerbation of chronic bronchitis and acute bacterial sinusitis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Other warnings: hypersensitivity reactions including anaphylaxis, hepatotoxicity (severe, sometimes fatal), aortic aneurysm and dissection, QT prolongation and torsade de pointes (avoid with known QT prolongation, uncorrected hypokalaemia and class IA/III antiarrhythmics), blood glucose disturbances, photosensitivity, Clostridioides difficile-associated diarrhoea, and CNS effects including seizures, increased intracranial pressure and psychiatric reactions.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• WarfarinEffects of warfarin may be enhanced; monitor prothrombin time, INR and watch for bleeding.DailyMed (U.S. National Library of Medicine)
• Antidiabetic agentsBlood glucose disturbances including symptomatic hyper- and hypoglycaemia; carefully monitor blood glucose.DailyMed (U.S. National Library of Medicine)
• TheophyllineClosely monitor theophylline levels and adjust dosage; adverse reactions including seizures may occur with or without elevated theophylline levels.DailyMed (U.S. National Library of Medicine)

• Pregnancy Category C (labeling of this injection SPL): no adequate and well-controlled studies in pregnant women; levofloxacin was not teratogenic in rats and rabbits; use during pregnancy only if the potential benefit justifies the potential risk to the fetus.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Levofloxacin is excreted in human milk; because of the potential for serious adverse reactions in nursing infants, decide whether to discontinue nursing or the drug.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Levofloxacin: Levofloxacin inhibits bacterial topoisomerase IV and DNA gyrase, enzymes required for DNA replication, transcription, repair and recombination (US label).