سعر ليفوكسين 250 مجم 5 اقراص 2022

Levofloxacin 250 mg film-coated tablets, pack of 5.

• Uncomplicated urinary tract infection (adults), 250 mg once daily for 3 days; reserve fluoroquinolones for patients without alternative treatment options.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Complicated urinary tract infection or acute pyelonephritis (adults), 250 mg once daily for 10 days.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (at least 3%): nausea, headache, diarrhoea, insomnia, constipation and dizziness.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to levofloxacin or other quinolone antibacterials.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fluoroquinolones are associated with disabling and potentially irreversible serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy and CNS effects - discontinue immediately if these occur; may exacerbate muscle weakness in myasthenia gravis (avoid); reserve for patients without alternative options for uncomplicated UTI, acute bacterial exacerbation of chronic bronchitis and acute bacterial sinusitis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Other warnings: hypersensitivity reactions (including anaphylaxis), hepatotoxicity, aortic aneurysm and dissection, Clostridioides difficile-associated diarrhoea, QT prolongation, blood glucose disturbances and photosensitivity/phototoxicity.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Multivalent cation-containing products (Mg/Al antacids, sucralfate, iron, zinc, didanosine)Reduce levofloxacin absorption; take levofloxacin at least 2 hours before or after.DailyMed (U.S. National Library of Medicine)
• WarfarinEnhanced warfarin effect; monitor prothrombin time/INR and for bleeding.DailyMed (U.S. National Library of Medicine)
• Antidiabetic agentsBlood glucose disturbances (hypo- and hyperglycaemia); monitor blood glucose carefully.DailyMed (U.S. National Library of Medicine)

• Available data from published studies of levofloxacin use in pregnancy have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Levofloxacin is present in human milk; because of the potential for serious adverse reactions, a lactating woman may consider pumping and discarding milk during treatment and for 2 days after the last dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Levofloxacin: Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV.