سعر ليوميتاسين 50مجم/2مل 6 امبولات مجفدة 2023

Liometacen indometacin 50 mg lyophilised powder for injection with 2 mL solvent, 6 ampoules (El Nile under licence from Chiesi, Italy); NSAID.

• Known hypersensitivity to indometacin or any component.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• History of asthma, urticaria or allergic-type reactions after aspirin or other NSAIDs.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Setting of coronary artery bypass graft (CABG) surgery.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Boxed warning (NSAIDs): increased risk of serious cardiovascular thrombotic events (MI, stroke), which may occur early and increase with duration.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Boxed warning (NSAIDs): serious gastrointestinal bleeding, ulceration and perforation can occur at any time without warning; elderly patients and those with prior ulcer disease or GI bleeding are at greater risk.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Anticoagulants (e.g. warfarin)Synergistic effect on bleeding; increased risk of serious bleeding compared with either drug alone.DailyMed (U.S. National Library of Medicine)
• Lithium; digoxin; cyclosporine; ACE inhibitors, ARBs and beta-blockersRaises lithium levels and digoxin concentration/half-life (monitor levels), may increase cyclosporine nephrotoxicity, and may diminish antihypertensive effects.DailyMed (U.S. National Library of Medicine)

• NSAIDs can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction with oligohydramnios: limit dose and duration between about 20 and 30 weeks and avoid from about 30 weeks of gestation.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• May be present in human milk at low levels (estimated about 0.27-0.5% of the maternal weight-adjusted dose); weigh benefits of breastfeeding against maternal need.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Indometacin: Inhibits cyclo-oxygenase and prostaglandin synthesis.