سعر لوميكس 400مجم 10 اقراص 2023

Lomex (Sigma, Egypt): lomefloxacin 400 mg tablets, pack of 10; a once-daily oral fluoroquinolone antibacterial.

• Acute bacterial exacerbation of chronic bronchitis (mild to moderate) caused by Haemophilus influenzae or Moraxella catarrhalis; not indicated for empiric treatment when Streptococcus pneumoniae is a probable pathogen.Population: AdultsU.S. Food and Drug Administration (Drugs@FDA)
• Uncomplicated urinary tract infections (cystitis) and complicated urinary tract infections caused by susceptible bacteria.Population: AdultsU.S. Food and Drug Administration (Drugs@FDA)
• Preoperative prophylaxis to reduce urinary tract infection after transrectal prostate biopsy or transurethral surgical procedures.Population: AdultsU.S. Food and Drug Administration (Drugs@FDA)

• Most frequent in US clinical trials: headache 3.6%, nausea 3.5%, photosensitivity 2.3%, dizziness 2.1%, diarrhoea 1.4%, abdominal pain 1.2%.International label, same formulation · U.S. Food and Drug Administration (Drugs@FDA)

• Hypersensitivity to lomefloxacin or any member of the quinolone class of antimicrobial agents.International label, same formulation · U.S. Food and Drug Administration (Drugs@FDA)

• Phototoxicity: moderate to severe phototoxic reactions can occur; avoid direct or indirect sunlight and artificial UV light during treatment and for several days after; stop at the first sign of phototoxicity.International label, same formulation · U.S. Food and Drug Administration (Drugs@FDA)
• Convulsions reported with lomefloxacin (possibly higher seizure risk than other quinolones); quinolones can cause increased intracranial pressure, toxic psychoses and CNS stimulation; use with caution in known or suspected CNS disorders or seizure risk factors. Lomefloxacin can cause dizziness; caution when driving.International label, same formulation · U.S. Food and Drug Administration (Drugs@FDA)
• Serious, occasionally fatal hypersensitivity (anaphylactic) reactions; discontinue at the first appearance of skin rash or other signs of hypersensitivity.International label, same formulation · U.S. Food and Drug Administration (Drugs@FDA)

• Antacids (magnesium/aluminium), sucralfate, didanosineReduce lomefloxacin absorption; do not take within 4 hours before or 2 hours after a lomefloxacin dose. Products containing iron, zinc or other minerals should be separated by at least 2 hours.U.S. Food and Drug Administration (Drugs@FDA)
• ProbenecidProbenecid slows renal elimination of lomefloxacin (AUC increased by about 63%).U.S. Food and Drug Administration (Drugs@FDA)
• WarfarinQuinolones may enhance the effect of warfarin; monitor prothrombin time.U.S. Food and Drug Administration (Drugs@FDA)

• No adequate and well-controlled studies in pregnant women; use during pregnancy only if the potential benefit justifies the potential risk to the fetus.International label, same formulation · U.S. Food and Drug Administration (Drugs@FDA)
• Excretion in human milk is unknown; because of the potential for serious adverse reactions in nursing infants, decide whether to discontinue nursing or the drug.International label, same formulation · U.S. Food and Drug Administration (Drugs@FDA)

• Lomefloxacin: Fluoroquinolone antibacterial; inhibits bacterial DNA gyrase (topoisomerase), blocking bacterial DNA replication.