سعر لوسيبروست 0.4 مجم 30 كبسولة 2022

Losiprost 0.4 mg by European Egyptian Pharmaceutical Industries / Pharma-Tech (Egypt): tamsulosin capsules, an alpha-1A blocker for urinary symptoms of benign prostatic hyperplasia.

• Treatment of the signs and symptoms of benign prostatic hyperplasia (BPH); not indicated for the treatment of hypertension.Population: Adult menDailyMed (U.S. National Library of Medicine)

• Most common (>=2% and more than placebo) with 0.4 mg or 0.8 mg: headache, dizziness, rhinitis, infection, abnormal ejaculation (8.4% at 0.4 mg, 18.1% at 0.8 mg vs 0.2% placebo), asthenia, back pain, diarrhoea, pharyngitis, chest pain, increased cough, somnolence, nausea, sinusitis, insomnia, decreased libido, tooth disorder and blurred vision.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to tamsulosin hydrochloride or any component of the capsules (reactions have included skin rash, urticaria, pruritus, angioedema and respiratory symptoms).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Postural hypotension with or without symptoms (dizziness, vertigo) and syncope may occur; avoid situations where injury could result. Should not be used with strong CYP3A4 inhibitors or other alpha-adrenergic blockers; caution with moderate CYP3A4 or CYP2D6 inhibitors and with warfarin. Priapism (rare); screen for prostate cancer before and during treatment; intraoperative floppy iris syndrome during cataract or glaucoma surgery; sulfa allergy (rare allergic reactions reported).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A4 inhibitors (e.g. ketoconazole); moderate CYP3A4 and CYP2D6 inhibitorsIncrease tamsulosin exposure; do not use with strong CYP3A4 inhibitors; use with caution with moderate inhibitors.DailyMed (U.S. National Library of Medicine)
• Other alpha-adrenergic blocking agentsShould not be used in combination (expected additive effects, risk of hypotension).DailyMed (U.S. National Library of Medicine)
• PDE5 inhibitorsCaution: alpha-blockers and PDE5 inhibitors both lower blood pressure, with possible symptomatic hypotension.DailyMed (U.S. National Library of Medicine)

• Tamsulosin hydrochloride is not indicated for use in women; no adequate human data; no adverse developmental effects in rat or rabbit studies.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Tamsulosin: Blocks alpha-1 adrenoceptors (predominantly alpha-1A) in the prostate, prostatic capsule, prostatic urethra and bladder neck, relaxing smooth muscle and improving urine flow and BPH symptoms.