سعر ماكسدنير 300 مجم كبسولات 2024

Cefdinir 300 mg capsules, pack of 10; third-generation cephalosporin antibiotic (Chemipharm, Egypt).

• Community-acquired pneumonia (H. influenzae, H. parainfluenzae, S. pneumoniae penicillin-susceptible, M. catarrhalis)Population: Adults and adolescents (13 years and older)DailyMed (U.S. National Library of Medicine)
• Acute exacerbations of chronic bronchitis (H. influenzae, H. parainfluenzae, S. pneumoniae penicillin-susceptible, M. catarrhalis)Population: Adults and adolescents (13 years and older)DailyMed (U.S. National Library of Medicine)
• Acute maxillary sinusitis (H. influenzae, S. pneumoniae penicillin-susceptible, M. catarrhalis)Population: Adults and adolescents (13 years and older)DailyMed (U.S. National Library of Medicine)

• Most common adverse reactions in adult and adolescent trials (capsules): diarrhoea (15%), vaginal moniliasis (4% of women), nausea (3%), headache (2%), abdominal pain (1%) and vaginitis (1% of women).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Contraindicated in patients with known allergy to the cephalosporin class of antibiotics.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Before therapy, ask about previous hypersensitivity to cefdinir, other cephalosporins, penicillins or other drugs; cross-hypersensitivity among beta-lactams occurs in up to 10% of penicillin-allergic patients. Stop the drug if an allergic reaction occurs; serious acute reactions may need epinephrine and other emergency measures.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea has been reported with nearly all antibacterials, including cefdinir, and may range from mild diarrhoea to fatal colitis; consider it in any patient with diarrhoea after antibiotic use.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Prolonged use may result in overgrowth of resistant organisms; prescribe only for proven or strongly suspected bacterial infections. Use with caution in patients with a history of colitis.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Antacids containing aluminium or magnesiumReduce cefdinir absorption; take cefdinir at least 2 hours before or after the antacid.DailyMed (U.S. National Library of Medicine)
• Iron supplements and iron-fortified foodsIron reduces cefdinir absorption; take cefdinir at least 2 hours before or after iron supplements. Reddish stools have been reported with iron-containing products.DailyMed (U.S. National Library of Medicine)
• ProbenecidInhibits renal excretion of cefdinir, roughly doubling AUC and increasing peak plasma levels.DailyMed (U.S. National Library of Medicine)

• Animal reproduction studies showed no teratogenicity; there are no adequate and well-controlled studies in pregnant women, so cefdinir should be used during pregnancy only if clearly needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• After single 600 mg doses, cefdinir was not detected in human breast milk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cefdinir: Bactericidal; like other cephalosporins it inhibits bacterial cell-wall synthesis, and it is stable in the presence of some beta-lactamases (US label).