سعر موسلجيكس 20 كبسولة 200 مجم + 400 مجم 2024

Muslgix capsules, pack of 20 (Pharopharma / EMA Pharm, Egypt): oral fixed-dose combination of the NSAID ibuprofen and the centrally acting skeletal muscle relaxant methocarbamol (hard capsules, 200 mg + 400 mg per Vademecum's Egypt listing), described by Egyptian directories for the symptomatic treatment of musculoskeletal conditions with painful muscle spasm, sprains and strains.

• Ibuprofen: gastrointestinal complaints are the most frequent adverse reactions (e.g. nausea, epigastric pain, heartburn, diarrhoea, abdominal distress, vomiting, indigestion, constipation); serious GI ulceration and bleeding can occur.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Methocarbamol: reported adverse reactions include anaphylactic reaction, angioneurotic oedema, fever, headache, bradycardia, flushing, hypotension, syncope, dyspepsia, jaundice, nausea and vomiting, leukopenia, hypersensitivity reactions, and nervous-system effects such as amnesia, confusion, diplopia, dizziness, drowsiness, insomnia, incoordination, nystagmus, sedation and seizures.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Ibuprofen: contraindicated in known hypersensitivity to ibuprofen, in patients who have had asthma, urticaria or allergic-type reactions after aspirin or other NSAIDs, and in the setting of coronary artery bypass graft (CABG) surgery.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Methocarbamol: contraindicated in patients hypersensitive to methocarbamol or to any of the tablet components.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal; the risk may occur early in treatment and may increase with duration of use.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration and perforation of the stomach or intestines, which can be fatal, can occur at any time without warning symptoms, and are more likely in the elderly.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• NSAIDs can cause new or worsened hypertension and may impair the response to thiazide or loop diuretics; monitor blood pressure closely at the start of and during treatment.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Long-term NSAID administration has resulted in renal papillary necrosis and other renal injury; in patients whose renal perfusion depends on prostaglandins, an NSAID may precipitate overt renal decompensation.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Methocarbamol may have a general CNS-depressant effect: patients should be cautioned about combined effects with alcohol and other CNS depressants, and that drowsiness or dizziness may impair their ability to drive or operate machinery.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Low-dose aspirinIbuprofen can interfere with the antiplatelet effect of low-dose aspirin, particularly when ibuprofen is dosed before aspirin.DailyMed (U.S. National Library of Medicine)
• Warfarin-type (coumarin) anticoagulantsBleeding has been reported when ibuprofen and other NSAIDs were given with coumarin-type anticoagulants; use caution.DailyMed (U.S. National Library of Medicine)
• ACE inhibitorsNSAIDs may diminish the antihypertensive effect of ACE inhibitors.DailyMed (U.S. National Library of Medicine)
• LithiumIbuprofen raised plasma lithium levels (mean minimum concentration +15%) and reduced renal lithium clearance (-19%); observe for lithium toxicity.DailyMed (U.S. National Library of Medicine)
• Pyridostigmine / anticholinesterase agentsMethocarbamol may inhibit the effect of pyridostigmine bromide; use with caution in myasthenia gravis patients receiving anticholinesterase agents.DailyMed (U.S. National Library of Medicine)
• Alcohol and other CNS depressantsCombined CNS-depressant effects with methocarbamol; patients should be cautioned.DailyMed (U.S. National Library of Medicine)

• Safe use of methocarbamol in pregnancy has not been established; there are reports of fetal and congenital abnormalities after in utero exposure, so it should not be used in women who are or may become pregnant, particularly in early pregnancy, unless the potential benefits outweigh the hazards.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• It is not known whether ibuprofen is excreted in human milk; because of potential serious adverse reactions in nursing infants, decide whether to discontinue nursing or the drug, taking into account its importance to the mother.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Methocarbamol and/or its metabolites are excreted in the milk of dogs; it is not known whether they are excreted in human milk, so caution should be exercised in nursing women.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

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