سعر ناجلوفيك 750مجم 10 اقراص 2025

Naglovic 750 mg film-coated tablets, pack of 10 (Jedco International > El Razy Pharmaceuticals, Egypt): oral levofloxacin 750 mg fluoroquinolone antibiotic.

• Nosocomial pneumonia, community-acquired pneumonia, complicated skin and skin-structure infections, complicated UTI/acute pyelonephritis and acute bacterial sinusitis (750 mg regimens), due to designated susceptible bacteriaPopulation: Adults (18 years and older)DailyMed (U.S. National Library of Medicine)

• Most common (>= 3%): nausea, headache, diarrhoea, insomnia, constipation and dizziness.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to levofloxacin or other quinolone antibacterials.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: disabling and potentially irreversible serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy and CNS effects (discontinue immediately); may exacerbate muscle weakness in myasthenia gravis (avoid); reserve for patients without alternatives in uncomplicated UTI, acute bacterial exacerbation of chronic bronchitis and acute bacterial sinusitis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• QT prolongation and rare torsade de pointes: avoid in known QT prolongation, uncorrected hypokalaemia and with class IA or III antiarrhythmics.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Other serious reactions: hypersensitivity, severe skin reactions, hepatotoxicity, aortic aneurysm and dissection, Clostridioides difficile-associated diarrhoea, blood glucose disturbances and photosensitivity.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Antacids (Mg/Al), sucralfate, metal cations (iron), zinc-containing multivitamins, didanosineChelation may substantially reduce levofloxacin absorption; separate administration by at least 2 hours.DailyMed (U.S. National Library of Medicine)
• Class IA (quinidine, procainamide) and class III (amiodarone, sotalol) antiarrhythmicsAdditive QT prolongation; avoid concomitant use.DailyMed (U.S. National Library of Medicine)

• Published case reports and observational studies have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; not teratogenic in rats and rabbits.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Present in human milk; for most indications consider pumping and discarding milk during treatment and for 2 days after the last dose, or advise not to breastfeed during this period.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Levofloxacin: Inhibits bacterial topoisomerase IV and DNA gyrase (type II topoisomerases) required for DNA replication, transcription, repair and recombination (US label).