سعر نازوبكترا 125/50مكجم بخاخ للأنف 2024

• Moderate to severe seasonal and perennial allergic rhinitis when intranasal antihistamine or glucocorticoid monotherapy is insufficientPopulation: Adults and adolescents 12 years and overelectronic medicines compendium (emc)
• Seasonal allergic rhinitisPopulation: Adults and children 6 years and older (US)DailyMed (U.S. National Library of Medicine)

• Reported reactions include epistaxis, headache, dysgeusia (unpleasant taste; common, often from tilting the head back) and unpleasant smell, nasal discomfort, sneezing, nasal dryness, cough, dry throat, dizziness, somnolence, nausea, rash, pruritus and fatigue; rarely hypersensitivity, nasal septal perforation, glaucoma or cataract.International label, equivalent formulation · electronic medicines compendium (emc)

• Hypersensitivity to the active substances or any excipient.International label, equivalent formulation · electronic medicines compendium (emc)

• Avoid with ritonavir unless benefit outweighs risk (Cushing's syndrome and adrenal suppression reported); systemic corticosteroid effects are possible at high or prolonged doses (adrenal suppression, growth retardation, cataract, glaucoma); monitor growth in adolescents on prolonged treatment; caution in severe liver disease; fatigue or dizziness may impair driving (alcohol may add).International label, equivalent formulation · electronic medicines compendium (emc)

• Ritonavir and other CYP3A4 inhibitors incl. cobicistat-containing productsGreatly increased fluticasone exposure with systemic corticosteroid effects; avoid unless benefit outweighs risk, then monitor.electronic medicines compendium (emc)
• Potent CYP3A4 inhibitors (e.g. ketoconazole)Potential for increased systemic fluticasone propionate exposure; care advised.electronic medicines compendium (emc)
• Sedatives / CNS depressants and alcoholSedative effect of azelastine may be enhanced.electronic medicines compendium (emc)

• No or limited data in pregnant women; use only if the potential benefit justifies the potential risk to the foetus.International label, equivalent formulation · electronic medicines compendium (emc)
• Unknown whether excreted in milk; use only if the potential benefit justifies the potential risk to the infant.International label, equivalent formulation · electronic medicines compendium (emc)

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