سعر نيموديبين 30 مجم 30 قرص 2022

Nimodipine 30 mg tablets, pack of 30 (Pharco).

• Prevention of ischaemic neurological deficits following aneurysmal subarachnoid haemorrhage.Population: Adultselectronic medicines compendium (eMC)

• Common: hypotension, headache, flushing, GI symptoms, oedema; less common: tachycardia, rash.International label, same formulation · electronic medicines compendium (eMC)

• Hypersensitivity to nimodipine or excipients; concomitant use with rifampicin (strong induction) contraindicated in some EU labels; do not use oral nimodipine IV (never give oral liquid/capsule contents intravenously — fatal).International label, same formulation · electronic medicines compendium (eMC)

• Monitor blood pressure; caution in cerebral oedema / raised ICP; avoid grapefruit; interactions with CYP3A4 inhibitors/inducers and other antihypertensives.International label, same formulation · electronic medicines compendium (eMC)

• CYP3A4 inhibitors (e.g. macrolides, azole antifungals) / grapefruit juiceMajorMay increase nimodipine plasma concentrations and hypotensive effect. Management: Avoid grapefruit; use caution / monitor BP with strong CYP3A4 inhibitors.electronic medicines compendium (eMC)

• Not recommended in pregnancy unless clearly necessary; animal data and limited human experience — benefit-risk assessment required.International label, same formulation · electronic medicines compendium (eMC)
• Nimodipine is excreted in breast milk; breastfeeding not recommended during treatment in some EU labels.International label, same formulation · electronic medicines compendium (eMC)

• Nimodipine: Blocks L-type calcium channels in vascular smooth muscle with preferential cerebral vessel effect.