سعر نيتروماك ريتارد 5مجم 30 كبسول 2024

Nitromak retard 5 mg nitroglycerin sustained-release capsules (October Pharma, Egypt), box of 30; oral long-acting nitrate for angina prophylaxis.

• Headache (most common, may be severe and recurrent), transient light-headedness, hypotension; uncommon syncope, crescendo angina, rebound hypertension; rare allergic reactions.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Allergy to nitroglycerin; concomitant PDE-5 inhibitors (sildenafil, tadalafil, vardenafil) or soluble guanylate cyclase stimulators such as riociguat.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Benefit in acute myocardial infarction or congestive heart failure not established and capsules are not recommended there because effects are hard to terminate. Severe hypotension, particularly upright, may occur even with small doses; tolerance and cross-tolerance to other nitrates may develop.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• PDE-5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil)Contraindicated: PDE-5 inhibitors amplify the vasodilatory effect of nitrates and can cause severe hypotension, syncope or myocardial ischaemia.DailyMed (U.S. National Library of Medicine)
• Riociguat (soluble guanylate cyclase stimulator)Contraindicated: concomitant use can cause hypotension.DailyMed (U.S. National Library of Medicine)

• Animal reproduction studies not conducted; unknown whether it causes fetal harm. Give to a pregnant woman only if clearly needed.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Unknown whether excreted in human milk; use with caution in nursing women.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Nitroglycerin (glyceryl trinitrate): Nitroglycerin forms nitric oxide, which activates guanylate cyclase and raises cyclic GMP in vascular smooth muscle, causing vasodilatation (venous more than arterial) (US Nitrolingual label 12.1).