سعر نورموليبسي 75مجم 20 كبسولة 2024

Pregabalin 75 mg capsules, pack of 20 (EIPICO, Egypt); gabapentinoid for neuropathic pain and adjunctive treatment of partial-onset seizures.

• Neuropathic pain associated with diabetic peripheral neuropathyPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Postherpetic neuralgiaPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy for partial-onset seizuresPopulation: Patients 1 month of age and olderDailyMed (U.S. National Library of Medicine)

• Most common in adults (>=5% and twice placebo): dizziness, somnolence, dry mouth, oedema, blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to pregabalin or any of its components (angioedema and hypersensitivity reactions have occurred).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Angioedema (possibly life-threatening) and hypersensitivity reactions: discontinue immediately.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Antiepileptic drugs, including pregabalin, increase the risk of suicidal thoughts or behaviour.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Abrupt or rapid discontinuation may increase seizure risk and cause withdrawal symptoms; taper gradually over at least 1 week.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CNS depressants (e.g. opioids)Respiratory depression may occur when pregabalin is used with concomitant CNS depressants; monitor and adjust dosage.DailyMed (U.S. National Library of Medicine)

• Observational studies suggest a possible small increase in the overall rate of major birth defects, without a consistent pattern; data on miscarriage and other outcomes are insufficient. A North American pregnancy registry exists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Pregabalin is present in breast milk (about 76% of maternal plasma; infant dose about 7% of maternal dose on a mg/kg basis); animal data suggest a potential tumorigenicity risk to the breastfed infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pregabalin: Binds with high affinity to the alpha2-delta auxiliary subunit of voltage-gated calcium channels in CNS tissue; does not bind GABA-A/GABA-B or benzodiazepine receptors (US label).