سعر بنيسيد ط.م. 1200000 وحدة فيال 1,200,000 units 2023

Long-acting depot penicillin (benzathine benzylpenicillin 1,200,000 units) vial for deep intramuscular injection.

• Mild-to-moderate upper respiratory infections due to susceptible group A streptococciDailyMed (U.S. National Library of Medicine)
• Syphilis, yaws, bejel and pintaDailyMed (U.S. National Library of Medicine)
• Prophylaxis of rheumatic fever and/or chorea; follow-up prophylaxis against rheumatic heart disease and acute glomerulonephritisDailyMed (U.S. National Library of Medicine)

• History of a previous hypersensitivity reaction to any penicillin.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: not for intravenous use; inadvertent IV administration has been associated with cardiorespiratory arrest and death.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Serious and occasionally fatal anaphylactic reactions have occurred with penicillins, more likely with a history of penicillin or multiple allergen sensitivity; cross-reactions with cephalosporins reported. Ask about prior reactions before use.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• TetracyclineBacteriostatic tetracycline may antagonise the bactericidal effect of penicillin; avoid concurrent use.DailyMed (U.S. National Library of Medicine)
• ProbenecidProbenecid increases and prolongs serum penicillin levels by inhibiting renal tubular secretion.DailyMed (U.S. National Library of Medicine)

• Animal reproduction studies with penicillin G showed no fetal harm and human experience has not shown adverse fetal effects, but there are no adequate controlled studies; use in pregnancy only if clearly needed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Soluble penicillin G (the hydrolysate) is excreted in breast milk; use caution in nursing women.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Benzathine benzylpenicillin: Slowly released from the IM depot and hydrolysed to penicillin G, which inhibits bacterial cell-wall synthesis (bactericidal), giving low but very prolonged serum levels.