سعر بيومبرايد 4/30مجم 30 قرص 2026

Piompride tablets (glimepiride 4 mg / pioglitazone 30 mg), pack of 30, by Averroes Pharma-Egypt.

• Adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes already treated with a thiazolidinedione and a sulfonylurea, or inadequately controlled on either alone; not for type 1 diabetes or ketoacidosis.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Initiation in established NYHA class III or IV heart failure; known hypersensitivity to pioglitazone, glimepiride or any component; history of allergic reaction to sulfonamide derivatives.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pioglitazone can cause dose-related fluid retention that may lead to or exacerbate congestive heart failure; observe for signs and consider discontinuation or dose reduction.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Macular oedema has been reported with thiazolidinediones; patients with visual symptoms should be referred promptly to an ophthalmologist.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Limited data are insufficient to determine a drug-associated risk; there are clinical considerations for fetal and neonatal adverse reactions (e.g. neonatal hypoglycaemia) and drug discontinuation if glimepiride is used in pregnancy.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No information on pioglitazone or glimepiride in human milk; both are present in rat milk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Glimepiride: Sulfonylurea insulin secretagogue that acts primarily by stimulating insulin release from functioning pancreatic beta cells (US Duetact label).
• Pioglitazone: Thiazolidinedione insulin sensitiser acting mainly by enhancing peripheral glucose utilisation; PPAR-gamma agonist (US Duetact label).