سعر بريسوثيوفال 160/25مجم 14 اقراص 2022

Fixed-dose combination of valsartan 160 mg and hydrochlorothiazide 25 mg film-coated tablets for hypertension, box of 14 tablets, by Debeiky (DBK Pharma), Egypt.

• Treatment of hypertension, to lower blood pressure (not indicated for initial therapy outside the label conditions; see US label)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common reasons for discontinuation were headache and dizziness; nasopharyngitis was the only adverse experience at >=2% and above placebo.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component; anuria; hypersensitivity to other sulfonamide-derived drugs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Do not coadminister aliskiren in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Correct volume depletion before starting (risk of hypotension).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Observe for fluid or electrolyte imbalance; monitor renal function and potassium in susceptible patients.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Possible exacerbation or activation of systemic lupus erythematosus; acute angle-closure glaucoma (hydrochlorothiazide).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• LithiumIncreased serum lithium and lithium toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• Potassium-sparing diuretics, potassium supplements, potassium-containing salt substitutesMay increase serum potassium.DailyMed (U.S. National Library of Medicine)

• Boxed warning (fetal toxicity): drugs acting on the renin-angiotensin system in the second and third trimesters reduce fetal renal function and increase fetal and neonatal morbidity and death; discontinue as soon as pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Valsartan is present in rat milk and hydrochlorothiazide is present in human milk; breastfeeding is not recommended during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Valsartan: Blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II at the AT1 receptor.
• Hydrochlorothiazide: Promotes renal excretion of sodium and chloride, reducing intravascular volume.