سعر راندابالين جل 30 جرام 0.1% 2024

Adapalene 0.1% topical gel, 30 g tube (Rexcel, Egypt); a topical retinoid-like anti-acne preparation.

• Cutaneous treatment of mild to moderate acne where comedones, papules and pustules predominate (face, chest or back).electronic medicines compendium (emc)

• Common: dry skin, skin irritation, skin burning sensation, erythema.International label, same formulation · electronic medicines compendium (emc)
• Uncommon: contact dermatitis, skin discomfort, sunburn, pruritus, skin exfoliation, acne flare. Post-marketing: allergic contact dermatitis, skin pain or swelling, application site burns, hypo-/hyperpigmentation, eyelid irritation/erythema/pruritus/swelling, anaphylactic reaction, angioedema.International label, same formulation · electronic medicines compendium (emc)

• Pregnancy and women planning a pregnancy.International label, same formulation · electronic medicines compendium (emc)
• Hypersensitivity to adapalene or to any of the excipients.International label, same formulation · electronic medicines compendium (emc)

• Discontinue if sensitivity or severe irritation occurs; reduce frequency or interrupt use if local irritation warrants. Avoid contact with eyes, mouth, angles of the nose and mucous membranes; do not apply to broken, sunburnt or eczematous skin or in severe acne involving large areas.International label, same formulation · electronic medicines compendium (emc)
• Minimise exposure to sunlight and UV irradiation during use.International label, same formulation · electronic medicines compendium (emc)
• The UK product contains methyl parahydroxybenzoate (may cause delayed allergic reactions) and propylene glycol 40 mg/g (may cause skin irritation); Egyptian excipients not verified.International label, same formulation · electronic medicines compendium (emc)

• Other retinoids or drugs with a similar mode of actionShould not be used concurrently with adapalene.electronic medicines compendium (emc)
• Peeling agents, abrasive cleansers, strong drying agents, astringents, alcoholic/aromatic irritantsMay produce additive irritant effects.electronic medicines compendium (emc)

• Contraindicated in pregnancy or in women planning a pregnancy; oral retinoids are associated with congenital abnormalities and, although topical exposure is low, treatment should be stopped if pregnancy occurs.International label, same formulation · electronic medicines compendium (emc)
• Can be used during breast-feeding (negligible systemic exposure); avoid applying to the chest to prevent contact exposure of the infant.International label, same formulation · electronic medicines compendium (emc)

• Adapalene: Retinoid-like compound that binds specific retinoic acid nuclear receptors; normalises differentiation of follicular epithelial cells, decreasing microcomedone formation, and has anti-inflammatory activity (UK Differin SmPC).