سعر ماربالين كريم 30 جم 0.1% 2022

Adapalene 0.1% topical cream in a 30 g tube by Marcyrl Pharmaceutical Industries, Egypt, for acne vulgaris.

• Topical treatment of acne vulgaris.Population: Patients 12 years and olderDailyMed (U.S. National Library of Medicine)

• Local cutaneous irritation: in controlled trials (N=285) mild erythema occurred in 38%, mild scaling in 35%, mild dryness in 42%; moderate reactions were less frequent and severe ones under 1%.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to adapalene or any component of the cream vehicle.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Erythema, dryness, scaling, burning or pruritus may occur, most likely in the first two to four weeks; reduce frequency or stop depending on severity.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Minimise exposure to sunlight and sunlamps during use.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• For external use only; avoid the eyes, lips, angles of the nose and mucous membranes; do not apply to cuts, abrasions, eczematous or sunburned skin; avoid wax epilation on treated skin.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Potentially irritating topical products; sulfur, resorcinol or salicylic acid preparationsUse other irritating topical products with caution; particular caution with sulfur, resorcinol or salicylic acid, and do not start adapalene until their effects have subsided.DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women; oral doses of 25 mg/kg or more were teratogenic in animals; use during pregnancy only if the potential benefit justifies the potential risk to the fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Not known whether adapalene is excreted in human milk; use with caution in nursing women.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Adapalene: Binds retinoic acid nuclear receptors and modulates cellular differentiation, keratinisation and inflammation; thought to normalise follicular epithelial differentiation and reduce microcomedone formation.