سعر ريكوفول 10مجم/مل 100مل امبول 2022

Propofol 10 mg/mL emulsion for intravenous injection/infusion, 100 mL, a short-acting general anaesthetic and sedative for hospital use.

• Induction of general anaesthesia.Population: Patients 3 years and olderDailyMed (U.S. National Library of Medicine)
• Maintenance of general anaesthesia.Population: Patients 2 months and olderDailyMed (U.S. National Library of Medicine)
• Initiation and maintenance of monitored anaesthesia care (MAC) sedation.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Common (>1%): bradycardia, arrhythmia, hypotension, hypertension, decreased cardiac output, movement, injection-site burning/stinging/pain, apnoea, rash, pruritus, hyperlipaemia, respiratory acidosis during weaning.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to propofol or any component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Allergy to eggs, egg products, soybeans or soy products.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Anaphylactic and anaphylactoid reactions have been reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Emulsion supports microbial growth: failure to follow aseptic handling has been associated with fever, infection, sepsis and death.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Propofol infusion syndrome (metabolic acidosis, rhabdomyolysis, hyperkalaemia, cardiac failure) reported, mainly with prolonged high-dose infusions (>5 mg/kg/h for >48 h).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Opioids, benzodiazepines and other CNS depressantsConcurrent premedication or sedatives increase anaesthetic/sedative effects and may cause more pronounced decreases in blood pressure and cardiac output; lower propofol doses may be required.DailyMed (U.S. National Library of Medicine)
• ValproateValproate increases blood levels of propofol; consider reducing the propofol dose.DailyMed (U.S. National Library of Medicine)
• Fentanyl (paediatric)Serious bradycardia has been reported in children given propofol with fentanyl.DailyMed (U.S. National Library of Medicine)

• Published studies in pregnant women have not identified a drug-associated risk of major birth defects; propofol crosses the placenta and may be associated with neonatal depression. Not recommended for obstetrics including caesarean section.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Propofol is present in human milk; consider the developmental and health benefits of breastfeeding with the mother's clinical need and potential adverse effects on the infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Propofol: Sedative-hypnotic; positive modulation of GABA-A receptor-mediated inhibition (label: mechanism not fully characterized).