سعر رسبادكس 2 مجم 2024

Risperidone 2 mg film-coated tablets (Marcyrl, Egypt), an atypical antipsychotic.

• Treatment of schizophrenia (adults and adolescents aged 13-17 years).DailyMed (U.S. National Library of Medicine)
• Bipolar I disorder: acute manic or mixed episodes, as monotherapy (adults and children/adolescents aged 10-17) or adjunctive to lithium or valproate (adults).DailyMed (U.S. National Library of Medicine)
• Irritability associated with autistic disorder in children and adolescents aged 5-17 years.Population: PediatricDailyMed (U.S. National Library of Medicine)

• Adult schizophrenia trials (2-8 mg/day): adverse reactions in >=2% included parkinsonism, nausea, constipation, dyspepsia, dry mouth, abdominal discomfort, fatigue, nasopharyngitis, blurred vision and back pain.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Pediatric autistic disorder trials: sedation (63%), increased appetite (44%), fatigue (31%), vomiting (20%), constipation (17%), drooling and tremor among the most common.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to risperidone, paliperidone or any excipient (anaphylaxis and angioedema reported).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased mortality in elderly patients with dementia-related psychosis; not approved for dementia-related psychosis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Warnings include cerebrovascular events in elderly dementia patients, neuroleptic malignant syndrome, tardive dyskinesia, metabolic changes (hyperglycaemia/diabetes, dyslipidaemia, weight gain), hyperprolactinaemia, orthostatic hypotension, falls, leukopenia/neutropenia/agranulocytosis, cognitive and motor impairment, seizures, dysphagia, priapism and body-temperature dysregulation.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Fluoxetine, paroxetine (CYP2D6 inhibitors)Reduce the risperidone dose; do not exceed 8 mg/day in adults when co-administered.DailyMed (U.S. National Library of Medicine)
• Carbamazepine and other enzyme inducers (phenytoin, rifampin, phenobarbital)Increase the risperidone dose up to double the usual dose; reduce when the inducer is stopped.DailyMed (U.S. National Library of Medicine)

• Published epidemiologic data have not established a drug-associated risk of major birth defects, miscarriage or adverse maternal/fetal outcomes; untreated schizophrenia or bipolar I disorder carries maternal risk. A pregnancy exposure registry exists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Risperidone and 9-hydroxyrisperidone pass into breast milk (relative infant dose 2.3-4.7%); sedation, failure to thrive, jitteriness and extrapyramidal symptoms reported in breastfed infants; monitor exposed infants.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Risperidone: Mechanism unclear; therapeutic activity may be mediated through combined dopamine D2 and serotonin 5-HT2 receptor antagonism (US label).