سعر سيجماتاكسيم 1جم وريد/عضل فيال 2025

Sigmataxim 1 g is an Egyptian cefotaxime 1 g powder for injection in a vial for IV/IM use (Rameda > Sigma); cefotaxime is a third-generation cephalosporin antibiotic.

• Serious infections caused by susceptible bacteria (respiratory, genitourinary, gynaecological, bacteraemia, skin, intra-abdominal, bone/joint, CNS)Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Perioperative prophylaxisPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most frequent: local injection-site reactions (4.3%), hypersensitivity such as rash, pruritus, fever, eosinophilia (2.4%), and gastrointestinal effects such as colitis, diarrhoea, nausea, vomiting (1.4%).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to cefotaxime sodium or other cephalosporins.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Inquire about previous hypersensitivity to cephalosporins, penicillins or other drugs; caution in type I penicillin allergy; discontinue if an allergic reaction occurs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea may occur; superinfection with non-susceptible organisms possible with prolonged use.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Leukopenia, neutropenia and rarely agranulocytosis may develop; monitor blood counts for courses longer than 10 days.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• ProbenecidProbenecid reduces cefotaxime clearance (about 50%) and raises its plasma concentrations.DailyMed (U.S. National Library of Medicine)

• Animal studies showed no embryotoxicity or teratogenicity; cefotaxime crosses the placenta; no well-controlled studies in pregnant women; use only if clearly needed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Excreted in human milk in low concentrations; use caution in nursing women.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Cefotaxime: Bactericidal; inhibits bacterial cell-wall synthesis and is active in the presence of some beta-lactamases (US CLAFORAN label).