سعر سيبراميسين 3م.و.د 10اقراص 2022

Spiramycin 3 million IU oral tablets, pack of 10; Pharopharma, Egypt.

• Documented group A beta-haemolytic streptococcal tonsillitis/pharyngitis, as an alternative to beta-lactams, particularly when these cannot be used.Population: AdultsAsafar (Moroccan medicines database based on AMMPS/ANAM data)
• Acute sinusitis, when beta-lactam treatment is impossible.Population: AdultsAsafar (Moroccan medicines database based on AMMPS/ANAM data)
• Superinfection of acute bronchitis and exacerbations of chronic bronchitis.Population: AdultsAsafar (Moroccan medicines database based on AMMPS/ANAM data)

• Common: abdominal pain, nausea, vomiting, diarrhoea, rash, transient dysgeusia; occasional transient paraesthesia; frequency unknown: QT prolongation, ventricular arrhythmia, anaphylaxis, vasculitis, severe skin reactions, cholestatic hepatitis, haemolytic anaemia (G6PD).International label, same formulation · Base de données publique des médicaments (ANSM, France)

• Hypersensitivity to spiramycin or to any of the excipients.International label, same formulation · Base de données publique des médicaments (ANSM, France)

• Severe cutaneous reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalised exanthematous pustulosis) have been reported; stop at the first signs and do not re-use spiramycin.International label, same formulation · Base de données publique des médicaments (ANSM, France)
• Very rare haemolytic anaemia in G6PD-deficient patients; use not recommended in this population.International label, same formulation · Base de données publique des médicaments (ANSM, France)
• QT prolongation reported with macrolides including spiramycin; caution in patients with risk factors (hypokalaemia/hypomagnesaemia, congenital long QT, heart disease, QT-prolonging drugs).International label, same formulation · Base de données publique des médicaments (ANSM, France)

• Torsadogenic (QT-prolonging) drugsIncreased risk of ventricular arrhythmias, notably torsades de pointes.Base de données publique des médicaments (ANSM, France)
• Levodopa/carbidopaInhibition of carbidopa absorption with lower levodopa levels; monitor and adjust levodopa.Base de données publique des médicaments (ANSM, France)
• Oral anticoagulants (vitamin K antagonists)INR changes reported with antibiotics including macrolides; monitor INR.Base de données publique des médicaments (ANSM, France)

• Spiramycin may be considered during pregnancy if needed; wide use in pregnancy has not shown malformative or fetotoxic effects to date.International label, same formulation · Asafar (Moroccan medicines database based on AMMPS/ANAM data)
• Passage into breast milk is significant and digestive disorders have been described in newborns; breastfeeding is not advised during treatment.International label, same formulation · Asafar (Moroccan medicines database based on AMMPS/ANAM data)

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