سعر ستاندازيل 40 مجم 10 قرص 2026

Standazil 40 mg tablets (Rameda, Egypt), pack of 10: azilsartan, an angiotensin II receptor blocker for hypertension.

• Treatment of hypertension in adults, to lower blood pressure (alone or with other antihypertensives).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common adverse reaction: diarrhoea (up to 2% with 80 mg vs 0.5% placebo). Others (>=0.3%): nausea, asthenia, fatigue, muscle spasm, dizziness, postural dizziness, cough. Postmarketing: rash, pruritus, angioedema.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Do not co-administer aliskiren-containing products in patients with diabetes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Fetal toxicity (boxed warning): discontinue when pregnancy is detected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic hypotension may occur in volume- or salt-depleted patients (e.g. high-dose diuretics); correct depletion first or start with 40 mg.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Impaired renal function: oliguria, progressive azotaemia and rarely acute renal failure may occur in patients whose renal function depends on the renin-angiotensin system (severe heart failure, renal artery stenosis, volume depletion).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• NSAIDs including COX-2 inhibitorsMay deteriorate renal function (possible acute renal failure) in elderly, volume-depleted or renally impaired patients and may attenuate the antihypertensive effect; monitor renal function.DailyMed (U.S. National Library of Medicine)
• ACE inhibitors, other ARBs, aliskiren (dual RAS blockade)Increased risk of hypotension, hyperkalaemia and renal impairment; avoid combined RAS inhibition; aliskiren contraindicated in diabetes and to be avoided if GFR <60 mL/min.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium and lithium toxicity reported; monitor lithium levels.DailyMed (U.S. National Library of Medicine)

• Boxed warning - fetal toxicity: drugs acting on the renin-angiotensin system can cause fetal injury and death; discontinue as soon as pregnancy is detected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Limited information on azilsartan in human milk (present in rat milk); breastfeeding is not recommended during treatment.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Azilsartan (directory; US reference product contains azilsartan medoxomil as potassium salt): Azilsartan medoxomil is a prodrug hydrolysed during absorption to azilsartan, which selectively blocks angiotensin II binding to the AT1 receptor, inhibiting its vasoconstrictor and aldosterone-secreting effects.