سعر املوديبين 5مجم 30 قرص 2025

Amlodipine 5 mg oral tablets (Amriya, Egypt), a dihydropyridine calcium channel blocker for hypertension and angina; 30 tablets (3 strips).

• Hypertension, to lower blood pressure (alone or with other antihypertensives), which reduces the risk of fatal and non-fatal cardiovascular events.Population: Adults and children 6-17 yearsDailyMed (U.S. National Library of Medicine)
• Symptomatic treatment of chronic stable angina and treatment of confirmed or suspected vasospastic (Prinzmetal's) angina.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Angiographically documented coronary artery disease without heart failure or EF <40%, to reduce hospitalisation for angina and coronary revascularisation.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Dose-related adverse reactions include oedema (10.8% at 10 mg vs 0.6% placebo), dizziness, flushing and palpitations; oedema is more frequent in women.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known sensitivity to amlodipine.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Symptomatic hypotension is possible, particularly in patients with severe aortic stenosis; because of gradual onset, acute hypotension is unlikely.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Worsening angina and acute myocardial infarction can occur after starting or increasing the dose, particularly in patients with severe obstructive coronary artery disease.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Titrate slowly in patients with severe hepatic impairment (extensive hepatic metabolism, prolonged half-life).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• SimvastatinAmlodipine increases simvastatin exposure; limit simvastatin to 20 mg daily.DailyMed (U.S. National Library of Medicine)
• Moderate and strong CYP3A inhibitorsIncrease amlodipine exposure; dose reduction may be required; monitor for hypotension and oedema.DailyMed (U.S. National Library of Medicine)
• Cyclosporine, tacrolimusAmlodipine may increase their exposure; monitor trough blood levels and adjust as appropriate.DailyMed (U.S. National Library of Medicine)

• Limited available data from post-marketing reports are insufficient to inform a drug-associated risk of major birth defects or miscarriage; untreated hypertension in pregnancy carries maternal and fetal risks.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Amlodipine is present in human milk; the estimated median relative infant dose is 4.2%. No adverse effects on breastfed infants have been observed; no information on milk production.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Amlodipine: Inhibits transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle, acting as a peripheral arterial vasodilator.