سعر تريتاس Tritace‏ 2.5مجم 14 قرص 2026

Ramipril 2.5 mg tablets, pack of 14 (Sanofi, Egyptian market).

• Safety profile includes persistent dry cough and reactions due to hypotension; serious reactions include angioedema, hyperkalaemia, renal or hepatic impairment, pancreatitis, severe skin reactions and neutropenia/agranulocytosis. Headache and dizziness are listed among common reactions.International label, same formulation · electronic medicines compendium (emc)

• Hypersensitivity to ramipril, any excipient or any other ACE inhibitor; history of angioedema (hereditary, idiopathic or previous ACE inhibitor/AIIRA angioedema).International label, same formulation · electronic medicines compendium (emc)
• Concomitant sacubitril/valsartan; extracorporeal treatments bringing blood into contact with negatively charged surfaces.International label, same formulation · electronic medicines compendium (emc)
• Significant bilateral renal artery stenosis or stenosis in a single functioning kidney; hypotensive or haemodynamically unstable states; second and third trimesters of pregnancy.International label, same formulation · electronic medicines compendium (emc)

• Risk of marked hypotension in patients with a strongly activated renin-angiotensin-aldosterone system (e.g. diuretic-treated, volume/salt depleted, severe hypertension, heart failure); initiate under supervision.International label, same formulation · electronic medicines compendium (emc)
• Angioedema (including intestinal angioedema) may occur; risk increased with mTOR inhibitors, vildagliptin or neprilysin inhibitors; discontinue and treat promptly.International label, same formulation · electronic medicines compendium (emc)
• Hyperkalaemia, hyponatraemia, neutropenia/agranulocytosis and renal function deterioration may occur; persistent dry cough is a known ACE inhibitor effect.International label, same formulation · electronic medicines compendium (emc)

• Potassium salts, heparin, potassium-retaining diuretics, trimethoprim/co-trimoxazole, tacrolimus, ciclosporinHyperkalaemia may occur; close monitoring of serum potassium required.electronic medicines compendium (emc)
• Lithium saltsACE inhibitors may reduce lithium excretion and increase lithium toxicity; monitor lithium levels.electronic medicines compendium (emc)
• NSAIDs and acetylsalicylic acidReduced antihypertensive effect; increased risk of worsening renal function and increased potassium.electronic medicines compendium (emc)

• Not recommended because of insufficient information; alternatives with better established safety are preferred, especially for newborn or preterm infants.International label, same formulation · electronic medicines compendium (emc)

• Ramipril: Prodrug hydrolysed to ramiprilat, which inhibits angiotensin-converting enzyme, reducing angiotensin II formation and aldosterone secretion.