سعر اموسار 50مجم 30 قرص 2022

Losartan potassium 50 mg film-coated tablets, pack of 30 (3 strips); angiotensin II receptor blocker for hypertension.

• Treatment of hypertension in adults and pediatric patients 6 years and older, to lower blood pressurePopulation: Adults and pediatric patients 6 years and olderDailyMed (U.S. National Library of Medicine)
• Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophy (evidence does not apply to Black patients)Population: AdultsDailyMed (U.S. National Library of Medicine)
• Treatment of diabetic nephropathy with elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertensionPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Adverse reactions in hypertension trials occurring more often than placebo include dizziness (3%), upper respiratory infection (8%), nasal congestion (2%) and back pain (2%).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Postmarketing reports include angioedema (including swelling of larynx, glottis, face, lips, pharynx and/or tongue), hepatitis, thrombocytopenia and hyperkalemia.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the product.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Co-administration with aliskiren in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning - fetal toxicity: drugs acting directly on the renin-angiotensin system can cause injury and death to the developing fetus; discontinue as soon as possible when pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic hypotension may occur in volume- or salt-depleted patients; correct depletion before starting or use a lower starting dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Changes in renal function including acute renal failure may occur (e.g., renal artery stenosis, severe heart failure, volume depletion); hyperkalemia may occur - monitor serum potassium.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Agents increasing serum potassium (potassium-sparing diuretics, potassium supplements, salt substitutes)May increase serum potassium; monitor potassium.DailyMed (U.S. National Library of Medicine)
• LithiumIncreases in serum lithium concentrations and lithium toxicity have been reported; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including selective COX-2 inhibitorsMay cause deterioration of renal function (including acute renal failure) in elderly, volume-depleted or renally impaired patients and may attenuate the antihypertensive effect; monitor renal function.DailyMed (U.S. National Library of Medicine)

• Use of drugs acting on the renin-angiotensin system during the second and third trimesters reduces fetal renal function and increases fetal and neonatal morbidity and death (oligohydramnios, skeletal deformations, hypotension, renal failure). Discontinue when pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• It is not known whether losartan is excreted in human milk; it is present in rat milk. Because of potential adverse effects on the nursing infant, decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Losartan: Losartan and its principal active metabolite selectively block binding of angiotensin II to the AT1 receptor, blocking its vasoconstrictor and aldosterone-secreting effects (US label).