سعر لوستابريسين 50مجم 21قرص 2022

Losartan potassium 50 mg film-coated tablets (Delta Pharma, Egypt); angiotensin II receptor blocker for hypertension.

• Hypertension in adults and pediatric patients 6 years and olderPopulation: Adults and children >= 6 yearsDailyMed (U.S. National Library of Medicine)
• Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophyPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Diabetic nephropathy with elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertensionPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Common in hypertension trials: dizziness, upper respiratory infection, nasal congestion and back pain.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Do not co-administer with aliskiren in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• BOXED WARNING - fetal toxicity: discontinue as soon as possible when pregnancy is detected; drugs acting on the renin-angiotensin system can cause injury and death to the developing fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hypotension may occur in volume- or salt-depleted patients; correct volume depletion before starting.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Changes in renal function including acute renal failure may occur, especially in patients dependent on the renin-angiotensin system or with renal artery stenosis.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Potassium supplements / potassium-sparing diuretics / salt substitutesMay increase serum potassium.DailyMed (U.S. National Library of Medicine)
• LithiumIncreases in serum lithium and lithium toxicity reported; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsMay worsen renal function (especially in elderly or volume-depleted patients) and attenuate the antihypertensive effect.DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm when used in the second and third trimesters (reduced fetal renal function, oligohydramnios, skeletal deformations, death); discontinue when pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether losartan passes into human milk; decide whether to discontinue nursing or the drug, considering the importance of the drug to the mother.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Losartan potassium: Losartan and its principal active metabolite selectively block binding of angiotensin II to the AT1 receptor, blocking its vasoconstrictor and aldosterone-secreting effects.