سعر جاسترودومينا 20 مجم 20 قرص 2024

Famotidine 20 mg tablets, 20 per pack, by Mup under licence from Almirall Prodesfarma (Spain).

• Active duodenal ulcer, active gastric ulcer, symptomatic nonerosive GERD and erosive esophagitis due to GERD.Population: Adults and pediatric patients weighing 40 kg or moreDailyMed (U.S. National Library of Medicine)
• Treatment of pathological hypersecretory conditions (e.g. Zollinger-Ellison syndrome) and reduction of the risk of duodenal ulcer recurrence.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Adverse reactions in at least 1% of patients in clinical trials: headache, dizziness and constipation. Postmarketing reports include arrhythmia, AV block, QT prolongation, cholestatic jaundice/hepatitis, agranulocytosis/pancytopenia, anaphylaxis/angioedema, rhabdomyolysis, confusion/agitation, interstitial pneumonia and SJS/TEN.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of serious hypersensitivity reactions (e.g. anaphylaxis) to famotidine or other histamine-2 (H2) receptor antagonists.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CNS adverse reactions (confusion, delirium, hallucinations, disorientation, agitation, seizures, lethargy) have been reported, mainly in elderly patients and patients with moderate-severe renal impairment; reduce the dose in renal impairment. Symptomatic response does not exclude gastric malignancy.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Drugs dependent on gastric pH for absorption (e.g. dasatinib, delavirdine, cefditoren, fosamprenavir)Reduced gastric acidity can lower absorption and efficacy; concomitant use with dasatinib, delavirdine mesylate, cefditoren and fosamprenavir is not recommended.DailyMed (U.S. National Library of Medicine)
• Tizanidine (CYP1A2 substrate)Famotidine is a weak CYP1A2 inhibitor and may increase tizanidine exposure (hypotension, bradycardia, excessive drowsiness); avoid concomitant use; if needed, monitor.DailyMed (U.S. National Library of Medicine)

• Available data with H2 blockers in pregnant women are insufficient to establish a drug-associated risk of major birth defects or miscarriage; no adverse developmental effects were seen in animal studies at high doses.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Limited data indicate famotidine is present in human milk; no adverse effects on breastfed infants have been reported and there are no data on milk production.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Famotidine: Competitive inhibitor of histamine-2 (H2) receptors that suppresses the acid concentration and volume of gastric secretion (US label).