سعر اريببريكس 30 مجم 20 قرص 2021

Aripiprex 30 mg 20 film-coated tablets (aripiprazole 30 mg), an atypical antipsychotic marketed in Egypt by Sigma > Andalous Pharma; 20 film-coated tablets.

• SchizophreniaPopulation: Adults and adolescents 13-17 yearsDailyMed (U.S. National Library of Medicine)
• Acute treatment of manic and mixed episodes associated with bipolar I disorder (monotherapy or adjunct to lithium or valproate)Population: Adults and pediatric patients 10-17 yearsDailyMed (U.S. National Library of Medicine)
• Adjunctive treatment of major depressive disorderPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most common in adults (>=10%): nausea, vomiting, constipation, headache, dizziness, akathisia, anxiety, insomnia and restlessness.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Most common in pediatric trials (>=10%): somnolence, headache, vomiting, extrapyramidal disorder, fatigue, increased appetite, insomnia, nausea, nasopharyngitis and weight increase.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity reaction to aripiprazole (reactions ranged from pruritus/urticaria to anaphylaxis).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: elderly patients with dementia-related psychosis treated with antipsychotics have an increased risk of death; aripiprazole is not approved for dementia-related psychosis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Boxed warning: antidepressants increased suicidal thoughts and behaviour in children, adolescents and young adults; monitor all patients for worsening and emergence of suicidality.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Cerebrovascular adverse events including stroke were increased in elderly patients with dementia-related psychosis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A4 inhibitors (e.g. itraconazole, clarithromycin) or strong CYP2D6 inhibitors (e.g. quinidine, fluoxetine, paroxetine)Increase aripiprazole exposure; reduce the aripiprazole dose.DailyMed (U.S. National Library of Medicine)
• Strong CYP3A4 inducers (e.g. carbamazepine, rifampin)Decrease aripiprazole exposure; increase the aripiprazole dose.DailyMed (U.S. National Library of Medicine)
• Antihypertensive drugsMay enhance the antihypertensive effect; monitor blood pressure.DailyMed (U.S. National Library of Medicine)

• Published epidemiologic data have not established a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; untreated psychiatric illness carries maternal risk. A pregnancy exposure registry exists.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Aripiprazole is present in human milk and may clinically reduce milk supply; monitor the breastfed infant for dehydration and poor weight gain.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Aripiprazole: Mechanism in schizophrenia and bipolar I disorder is not fully known; efficacy may be mediated by partial agonism at dopamine D2 and serotonin 5-HT1A receptors combined with antagonism at 5-HT2A receptors (US prescribing information).