سعر كونترامال 100مجم/مل نقط فم 10 مل 2022

Contramal 100mg/ml oral drops 10 ml: Tramadol (Sigma).

• Opioid analgesic for management of pain severe enough to require an opioid when alternatives are inadequate (US labeling).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Common adverse reactions include nausea, constipation, dry mouth, somnolence, dizziness, vomiting, headache and pruritus.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Contraindicated in children <12 years; postoperative use after tonsillectomy/adenoidectomy in <18 years; significant respiratory depression; acute/severe bronchial asthma; GI obstruction including paralytic ileus; concurrent MAOI or within 14 days; hypersensitivity to tramadol.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: addiction, abuse, misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal; CYP2D6 ultra-rapid metabolism risk; interactions with CNS depressants/benzodiazepines and alcohol; serotonin syndrome risk with serotonergic drugs.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Benzodiazepines / other CNS depressants / alcoholMajorConcomitant use increases risk of profound sedation, respiratory depression, coma and death.DailyMed (U.S. National Library of Medicine)
• MAO inhibitorsMajorDo not use tramadol with MAOIs or within 14 days — risk of serotonin syndrome and seizures.DailyMed (U.S. National Library of Medicine)

• May cause fetal harm; prolonged opioid use in pregnancy can result in neonatal opioid withdrawal syndrome. Breastfeeding not recommended.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Tramadol: Centrally acting analgesic; opioid (mu-receptor) activity plus inhibition of neuronal noradrenaline and serotonin reuptake; metabolised by CYP2D6 to an active metabolite (UK SmPC).