سعر ديكلوفيناك 50 مجم 20 قرص 2024

Declofenac 50mg 20 tab.: Diclofenac sodium (El nasr).

• Relief of signs and symptoms of osteoarthritis and rheumatoid arthritis (US delayed-release diclofenac sodium labeling).DailyMed (U.S. National Library of Medicine)
• Relief of signs and symptoms of ankylosing spondylitis (US delayed-release diclofenac sodium).DailyMed (U.S. National Library of Medicine)

• Common: abdominal pain, constipation, diarrhea, dyspepsia, flatulence, GI bleeding/ulcer, headache, dizziness, elevated liver enzymes, rash, edema, tinnitus.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to diclofenac; history of asthma, urticaria, or allergic-type reactions after aspirin or other NSAIDs; CABG perioperative pain; known hypersensitivity.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• NSAIDs cause increased risk of serious CV thrombotic events, MI, stroke; GI bleeding, ulceration, perforation; hepatotoxicity; hypertension; heart failure/edema; renal toxicity; anaphylactic reactions; serious skin reactions. Avoid in late pregnancy (from ~30 weeks) due to fetal renal dysfunction and premature closure of ductus arteriosus; limit use ~20–30 weeks.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Anticoagulants / antiplateletsMajorIncreased risk of serious bleeding when NSAIDs are coadministered with anticoagulants or antiplatelets.DailyMed (U.S. National Library of Medicine)
• ACE inhibitors / ARBs / diureticsModerateNSAIDs may diminish antihypertensive effect and worsen renal function, especially in elderly or volume-depleted patients.DailyMed (U.S. National Library of Medicine)
• Methotrexate / lithium / cyclosporineMajorNSAIDs may increase methotrexate, lithium and cyclosporine toxicity via reduced clearance.DailyMed (U.S. National Library of Medicine)

• NSAID use around 20 weeks or later in pregnancy may cause fetal renal dysfunction leading to oligohydramnios; avoid from about 30 weeks because of risk of premature closure of the fetal ductus arteriosus.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Diclofenac is excreted in human milk in small amounts; weigh benefits of breastfeeding against maternal need for the drug.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Diclofenac sodium: Inhibits cyclo-oxygenase (COX-1 and COX-2), reducing prostaglandin synthesis and thereby pain, inflammation and fever.