سعر روماتول 200 مجم 10 كبسولات 2026

Tolmetin 200 mg oral capsules (NSAID, pyrrole acetic acid derivative) by Sigma; pack of 10 capsules.

• Relief of signs and symptoms of rheumatoid arthritis (acute flares and long-term management)Population: AdultsDailyMed (US National Library of Medicine)
• Relief of signs and symptoms of osteoarthritisPopulation: AdultsDailyMed (US National Library of Medicine)
• Juvenile rheumatoid arthritisPopulation: Children 2 years and olderDailyMed (US National Library of Medicine)

• Most frequent (>1%): nausea (11%), dyspepsia, GI distress, abdominal pain, diarrhoea, flatulence, vomiting, constipation, gastritis, peptic ulcer; headache, asthenia, chest pain; elevated blood pressure, oedema; dizziness, drowsiness, depression; weight gain/loss; skin irritation; tinnitus, visual disturbance; small transient decreases in haemoglobin/haematocrit.General active-ingredient information · DailyMed (US National Library of Medicine)

• Known hypersensitivity to tolmetin.General active-ingredient information · DailyMed (US National Library of Medicine)
• History of asthma, urticaria or allergic-type reactions after aspirin or other NSAIDs (severe, rarely fatal anaphylactic reactions reported).General active-ingredient information · DailyMed (US National Library of Medicine)
• Setting of coronary artery bypass graft (CABG) surgery.General active-ingredient information · DailyMed (US National Library of Medicine)

• Boxed warning: NSAIDs increase the risk of serious cardiovascular thrombotic events (myocardial infarction, stroke), which can be fatal; the risk may occur early in treatment and may increase with duration of use.General active-ingredient information · DailyMed (US National Library of Medicine)
• Boxed warning: NSAIDs increase the risk of serious gastrointestinal bleeding, ulceration and perforation, which can be fatal and can occur without warning; elderly patients are at greater risk.General active-ingredient information · DailyMed (US National Library of Medicine)
• Renal effects: long-term NSAID use can cause renal papillary necrosis and other renal injury; acute interstitial nephritis with haematuria, proteinuria and occasionally nephrotic syndrome has been reported with tolmetin.General active-ingredient information · DailyMed (US National Library of Medicine)

• ACE inhibitors / angiotensin II antagonistsNSAIDs may diminish the antihypertensive effect; in elderly, volume-depleted or renally impaired patients the combination may worsen renal function (possible acute renal failure).DailyMed (US National Library of Medicine)
• Diuretics (furosemide, thiazides)NSAIDs can reduce the natriuretic effect of furosemide and thiazides; monitor for renal failure and diuretic efficacy.DailyMed (US National Library of Medicine)
• LithiumNSAIDs raise plasma lithium levels and reduce renal lithium clearance; observe for lithium toxicity.DailyMed (US National Library of Medicine)

• NSAID use can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment; limit dose and duration between about 20 and 30 weeks of gestation and avoid use from about 30 weeks onward.General active-ingredient information · DailyMed (US National Library of Medicine)
• Tolmetin is secreted in human milk; decide whether to discontinue nursing or the drug.General active-ingredient information · DailyMed (US National Library of Medicine)

• Tolmetin: Inhibits prostaglandin synthesis (cyclooxygenase inhibition), giving anti-inflammatory, analgesic and antipyretic effects.