سعر ابيجينت 20مجم/2مل 3 امبولات 2024

• Severe infections due to gentamicin-susceptible bacteria, notably urinary tract infections, endocarditis, meningitis (with other agents), osteo-articular infections and listeriosis, and bacteraemia; usually combined with another antibacterial such as a beta-lactam.Population: Adults and childrenEthiopian Food and Drug Authority (EFDA)
• Prophylaxis of post-operative/procedure-related infections caused by susceptible bacteria, according to official recommendations.Population: Adults and childrenEthiopian Food and Drug Authority (EFDA)

• Common: impaired renal function and allergic skin rash. Uncommon: blood dyscrasias, hypokalaemia, hypocalcaemia, hypomagnesaemia, nausea, vomiting and raised transaminases. Rare: vestibular disorders, hearing loss and tinnitus; very rare acute renal failure.International label, same product · Ethiopian Food and Drug Authority (EFDA)

• Hypersensitivity to aminoglycosides or excipients; myasthenia gravis; cirrhosis Child-Pugh B or C; subcutaneous administration; simultaneous use with another aminoglycoside.International label, same product · Ethiopian Food and Drug Authority (EFDA)

• Risk of nephrotoxicity and ototoxicity (vestibular and cochlear, hearing loss may be irreversible), increased with treatment longer than 5-7 days, renal impairment, age over 75, dehydration and concomitant loop diuretics or other oto/nephrotoxic drugs.International label, same product · Ethiopian Food and Drug Authority (EFDA)
• Neuromuscular blockade and respiratory depression may occur, especially with curare-type muscle relaxants or in patients with neuromuscular disorders; pseudomembranous colitis has been reported.International label, same product · Ethiopian Food and Drug Authority (EFDA)
• US labeling carries a boxed warning for potential nephrotoxicity, ototoxicity (vestibular and auditory) and neurotoxicity, with close clinical observation required.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Other aminoglycosidesSimultaneous use is contraindicated (additive oto- and nephrotoxicity).Ethiopian Food and Drug Authority (EFDA)
• Polymyxin B; botulinum toxinCombination not recommended: additive nephrotoxicity (polymyxin) or increased neuromuscular blockade (botulinum toxin).Ethiopian Food and Drug Authority (EFDA)
• Loop diuretics (e.g. furosemide)Increased risk of oto- and nephrotoxicity; monitor renal function and hydration.Ethiopian Food and Drug Authority (EFDA)

• Use in pregnancy should be limited to severe situations with no alternative; if used, hearing (cochleo-vestibular function) of the newborn should be checked.International label, same product · Ethiopian Food and Drug Authority (EFDA)
• Breastfeeding is possible during treatment (per the EFDA-approved SmPC).International label, same product · Ethiopian Food and Drug Authority (EFDA)

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