سعر جليميت 2.5/400 مجم 30 قرص مغلف 2024

Glimet 2.5/400 mg 30 film-coated tablets by Marcyrl Co.; active: Glibenclamide (glyburide) + Metformin.

• Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.Population: Adults with type 2 diabetesDailyMed (U.S. National Library of Medicine)

• Hypoglycemia, GI symptoms (diarrhea, nausea), upper respiratory infection, headache.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Renal disease or renal dysfunction; metabolic acidosis including diabetic ketoacidosis; concomitant bosentan; hypersensitivity to glyburide or metformin.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Lactic acidosis (metformin boxed warning); severe hypoglycemia from sulfonylurea; G6PD-related hemolytic anemia; cardiovascular mortality concern with oral hypoglycemics (historical).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Use in pregnancy only if clearly needed per US labeling; poorly controlled diabetes in pregnancy carries risks. Discuss breastfeeding with the label/pharmacist.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Glibenclamide: Stimulates insulin release from functioning pancreatic beta cells by binding the sulfonylurea receptor and closing ATP-sensitive potassium channels (US label).
• Metformin: Decreases hepatic glucose production, decreases intestinal glucose absorption and improves insulin sensitivity by increasing peripheral glucose uptake and utilization; insulin secretion remains unchanged (US label).