سعر ليبتيكيور 400 مجم 30 كبسولة 2025

Lepticure 400 mg capsules (gabapentin 400 mg), box of 30 capsules, Pharopharma; gabapentinoid antiepileptic also used for neuropathic pain.

• Management of postherpetic neuralgia in adults.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy for partial-onset seizures, with and without secondary generalization, in adults and pediatric patients 3 years and older with epilepsy.Population: Adults and children >=3 yearsDailyMed (U.S. National Library of Medicine)
• Treatment of epilepsy; reduces seizures caused by epilepsy (directory indication text).

• Most common adverse reactions: postherpetic neuralgia - dizziness, somnolence, peripheral edema; epilepsy (>=12 years) - somnolence, dizziness, ataxia, fatigue, nystagmus.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to gabapentin or its ingredients.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Drug reaction with eosinophilia and systemic symptoms (DRESS)/multiorgan hypersensitivity has been reported; discontinue if an alternative cause cannot be established.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Anaphylaxis and angioedema may occur; discontinue and seek immediate care.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Somnolence, sedation and dizziness may impair the ability to drive or operate machinery.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Opioids (e.g. morphine, hydrocodone)Risk of respiratory depression and sedation; morphine increased gabapentin exposure, and gabapentin decreased hydrocodone exposure.DailyMed (U.S. National Library of Medicine)
• Aluminum/magnesium hydroxide antacids (e.g. Maalox)Reduce gabapentin bioavailability by about 20%; take gabapentin at least 2 hours after the antacid.DailyMed (U.S. National Library of Medicine)
• Other CNS depressants (including alcohol)Additive CNS depression and risk of respiratory depression.DailyMed (U.S. National Library of Medicine)

• Available human data do not suggest an increased risk of major birth defects, but developmental toxicity was seen in animal studies; patients may enroll in the North American Antiepileptic Drug (NAAED) Pregnancy Registry.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Gabapentin is secreted in human milk; weigh the benefits of breastfeeding against the mother's need for the drug and possible effects on the infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Gabapentin: Structurally related to GABA but does not bind GABA receptors; binds with high affinity to the alpha2-delta subunit of voltage-gated calcium channels; the exact mechanism of its anticonvulsant and analgesic effects is unknown.