سعر لينيز 600 مجم 10 اقراص 2024

Linezolid 600 mg film-coated tablets, an oxazolidinone antibacterial for serious Gram-positive infections.

• Nosocomial pneumonia caused by Staphylococcus aureus (MSSA/MRSA) or Streptococcus pneumoniae.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Community-acquired pneumonia caused by susceptible Gram-positive bacteria.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Complicated skin and skin structure infections, including diabetic foot infections without osteomyelitis.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)

• Most common (> 5% of adult and/or paediatric patients): diarrhoea, vomiting, headache, nausea and anaemia.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to linezolid or any product component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Patients taking any monoamine oxidase inhibitor (A or B) or within two weeks of taking one.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Myelosuppression (anaemia, leukopenia, pancytopenia, thrombocytopenia); thrombocytopenia is more frequent in severe renal and moderate-to-severe hepatic impairment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Peripheral and optic neuropathy, mainly with treatment longer than 28 days; prompt ophthalmic evaluation if visual symptoms occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Serotonin syndrome with serotonergic agents; potential elevation of blood pressure with adrenergic agents; avoid large amounts of tyramine-rich food.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Monoamine oxidase inhibitorsContraindicated during and within two weeks of MAOI use.DailyMed (U.S. National Library of Medicine)
• Serotonergic agents (e.g., SSRIs, SNRIs, tricyclics, triptans)Risk of serotonin syndrome; monitor and consider discontinuation if symptoms occur.DailyMed (U.S. National Library of Medicine)
• Adrenergic agents (pseudoephedrine, phenylpropanolamine, dopamine, epinephrine)Reversible enhancement of pressor response; reduce initial doses of dopamine or epinephrine and titrate.DailyMed (U.S. National Library of Medicine)

• Published and postmarketing case reports have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes; embryo-fetal lethality was seen in mice at 6.5 times human exposure.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Linezolid is present in breast milk (infant dose about 6-9% of the therapeutic infant dose); monitor the breastfed infant for diarrhoea and vomiting.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Linezolid: Binds 23S rRNA of the bacterial 50S subunit and prevents formation of a functional 70S initiation complex (inhibits protein synthesis); also a reversible nonselective MAO inhibitor.