سعر مينيرين 10مكجم / جرعة بخاخ للانف 2022

Desmopressin acetate 10 micrograms per dose nasal spray (Minirin; Ferring Pharmaceuticals, marketed by Multipharma); listed as hospitals only. Pack size (number of sprays/volume) not stated by the sources opened.

• Antidiuretic replacement therapy in central diabetes insipidus in adults and children aged 4 years and older (not for nephrogenic diabetes insipidus or primary nocturnal enuresis).Population: Adults and children aged 4 years and olderDailyMed (U.S. NLM)

• Post-marketing reports include increased blood pressure, headache, nasal congestion, rhinitis, nosebleed, sore throat, cough, upper respiratory infections and nausea.International label, same formulation · DailyMed (U.S. NLM)

• Hypersensitivity to desmopressin acetate or any component (anaphylaxis reported).International label, same formulation · DailyMed (U.S. NLM)
• Renal impairment with creatinine clearance below 50 mL/min.International label, same formulation · DailyMed (U.S. NLM)
• Hyponatraemia or a history of hyponatraemia.International label, same formulation · DailyMed (U.S. NLM)

• Hyponatraemia/water intoxication, which can be fatal (seizures, coma, respiratory arrest): restrict fluid intake, especially in children and the elderly, and monitor serum sodium more often in at-risk patients.International label, same formulation · DailyMed (U.S. NLM)
• Changes in the nasal mucosa (scarring, oedema, atrophy, congestion) may alter absorption; use another formulation if absorption is unreliable.International label, same formulation · DailyMed (U.S. NLM)

• Tricyclic antidepressants, SSRIs, chlorpromazine, opiate analgesics, NSAIDs, lamotrigine, oxybutynin, carbamazepineIncrease the risk of water intoxication with hyponatraemia; monitor serum sodium more frequently.DailyMed (U.S. NLM)
• Other vasoconstrictorsMay elevate blood pressure; the desmopressin dose may need reduction.DailyMed (U.S. NLM)

• Decades of use in pregnancy have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes; placental transfer is poor.International label, same formulation · DailyMed (U.S. NLM)
• Transfer into breast milk is negligible; breastfeeding is not expected to cause clinically relevant infant exposure.International label, same formulation · DailyMed (U.S. NLM)

• Desmopressin acetate: Synthetic analogue of arginine vasopressin with strong V2 antidiuretic activity (increases renal water reabsorption).