سعر مينيرين ميلت 60 مكجم 30 قرص تحت اللسان 2024

Desmopressin 60 micrograms sublingual oral lyophilisate (Minirin Melt; Ferring Pharmaceuticals, marketed by Multipharma), 30 melts (3 strips of 10).

• Vasopressin-sensitive cranial diabetes insipidus and post-hypophysectomy polyuria/polydipsia.Population: Adults and childrenelectronic medicines compendium (emc), UK

• Headache, stomach pain and nausea; isolated allergic reactions; very rarely emotional disorders in children. Without fluid restriction, water retention/hyponatraemia (headache, nausea, vomiting, weight gain, convulsions in serious cases).International label, same formulation · electronic medicines compendium (emc), UK

• Cardiac insufficiency and other conditions requiring diuretic treatment; psychogenic polydipsia and alcohol abuse should be excluded before prescribing.International label, same formulation · electronic medicines compendium (emc), UK

• Care in reduced renal function and/or cardiovascular disease; prevent fluid overload in fluid/electrolyte imbalance and in patients at risk of raised intracranial pressure.International label, same formulation · electronic medicines compendium (emc), UK

• Tricyclic antidepressants, SSRIs, chlorpromazine, carbamazepine (SIADH-inducing drugs); NSAIDsMay add to the antidiuretic effect or cause water retention, increasing the risk of hyponatraemia.electronic medicines compendium (emc), UK
• LoperamideMay increase desmopressin plasma concentrations about 3-fold, raising the risk of water retention/hyponatraemia; other drugs slowing intestinal transport might act similarly.electronic medicines compendium (emc), UK

• Use with caution in pregnancy (limited data, rare malformations reported in 53 exposed pregnancies with diabetes insipidus); monitor blood pressure because of an increased risk of pre-eclampsia.International label, same formulation · electronic medicines compendium (emc), UK
• Amounts transferred into breast milk after high doses are far below those needed to influence diuresis.International label, same formulation · electronic medicines compendium (emc), UK

• Desmopressin acetate: Synthetic analogue of arginine vasopressin with strong V2 antidiuretic activity (increases renal water reabsorption).