سعر مينيرين ميلت 120مكجم 30 قرص تحت اللسان 2024

Desmopressin 120 micrograms sublingual oral lyophilisate (Minirin Melt; Ferring Pharmaceuticals, marketed by Multipharma), 30 melts (3 strips of 10).

• Primary nocturnal enuresis.Population: Children from 5 years and adults up to 65 yearselectronic medicines compendium (emc), UK
• Vasopressin-sensitive cranial diabetes insipidus and post-hypophysectomy polyuria/polydipsia.Population: Adults and childrenelectronic medicines compendium (emc), UK

• Hyponatraemia is the most serious reaction. Common: headache, abdominal pain, nausea, vomiting, diarrhoea; uncommon/rare: affect lability, aggression, nightmares, mood swings, somnolence, hypertension, bladder and urethral symptoms, peripheral oedema, fatigue, irritability.International label, same formulation · electronic medicines compendium (emc), UK

• Hypersensitivity; known or suspected cardiac insufficiency or other conditions requiring diuretics (use only with normal blood pressure); habitual or psychogenic polydipsia; age over 65 years; creatinine clearance below 50 ml/min; known hyponatraemia; SIADH.International label, same formulation · electronic medicines compendium (emc), UK

• Without fluid restriction, water retention and/or hyponatraemia may occur (headache, nausea/vomiting, weight gain, convulsions); interrupt treatment if these occur and during acute illnesses with fluid/electrolyte imbalance (fever, gastroenteritis, systemic infection).International label, same formulation · electronic medicines compendium (emc), UK
• Exclude severe bladder dysfunction and outlet obstruction before starting; elderly patients and those with low-normal serum sodium are at increased risk of hyponatraemia.International label, same formulation · electronic medicines compendium (emc), UK

• Tricyclic antidepressants, SSRIs, chlorpromazine, carbamazepine, sulfonylureas (especially chlorpropamide); NSAIDsAdditive antidiuretic effect or water retention, increasing the risk of hyponatraemia; restrict fluids and monitor sodium more often.electronic medicines compendium (emc), UK
• LoperamideMay increase desmopressin plasma concentrations about 3-fold (risk of water retention/hyponatraemia).electronic medicines compendium (emc), UK

• Use with caution in pregnancy (limited data); monitor blood pressure because of an increased risk of pre-eclampsia.International label, same formulation · electronic medicines compendium (emc), UK
• Amounts transferred into breast milk are considerably less than those required to influence diuresis.International label, same formulation · electronic medicines compendium (emc), UK

• Desmopressin acetate: Synthetic analogue of arginine vasopressin with strong V2 antidiuretic activity (increases renal water reabsorption).