سعر اوميجابرس 0.1مجم 2024

Desmopressin acetate 0.1 mg oral tablets, a synthetic vasopressin analogue (antidiuretic), Egyptian product.

• Antidiuretic replacement therapy in central diabetes insipidus and temporary polyuria/polydipsia after head trauma or pituitary surgeryPopulation: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Primary nocturnal enuresisPopulation: Patients aged 6 years and olderDailyMed (U.S. National Library of Medicine)

• Headache (4% vs 3% placebo in enuresis trials); transient mild AST increases in long-term diabetes insipidus studies; hyponatremia/water intoxication; rare hyponatremic convulsions with oxybutynin or imipramine.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to desmopressin acetate or any tablet component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hyponatremia or a history of hyponatremia.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Moderate to severe renal impairment (CrCl below 50 mL/min).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Potent antidiuretic: may cause water intoxication and hyponatremia, which can be fatal; fluid restriction and careful supervision are required, especially in children and the elderly.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Use with caution in habitual or psychogenic polydipsia, coronary artery insufficiency or hypertensive cardiovascular disease.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Tricyclic antidepressants, SSRIs, chlorpromazine, opiate analgesics, NSAIDs, lamotrigine, carbamazepineMay increase the risk of water intoxication with hyponatremia; co-administer with caution.DailyMed (U.S. National Library of Medicine)
• Other pressor agentsLarge doses should be combined with other pressor agents only with careful monitoring.DailyMed (U.S. National Library of Medicine)

• Animal studies showed no fetal harm; no adequate well-controlled human studies; a Swedish epidemiologic study found no increase in birth defects (low statistical power); use in pregnancy only if clearly needed. No uterotonic action at antidiuretic doses.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Not known whether excreted in human milk; a single study after intranasal 0.01 mg showed little if any change in milk levels; use with caution while nursing.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Desmopressin acetate: Synthetic analogue of arginine vasopressin with potent antidiuretic activity and very low pressor activity (US DDAVP label).