سعر ميلوباك 25مجم 20 قرص 2024

Mylobac 25 mg tablets (20 tablets; Pharopharma, Egypt): baclofen 25 mg, a centrally acting antispastic skeletal muscle relaxant.

• Suppression of voluntary muscle spasm in multiple sclerosisPopulation: AdultsMedicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia
• Spinal lesions (traumatic, infectious, degenerative, neoplastic or unknown origin) causing skeletal hypertonus or spastic/dyssynergic bladder dysfunctionPopulation: AdultsMedicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia

• Very common: sedation, somnolence, nausea. Common: confusion, hallucination, depression, insomnia, dizziness, headache, ataxia, tremor, visual/accommodation disorders, hypotension, GI upset, dry mouth, hyperhidrosis, rash, muscle weakness, myalgia, urinary frequency/enuresis/dysuria, respiratory depression, fatigue.International label, equivalent formulation · Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia
• US label: transient drowsiness (10-63%), dizziness and weakness (5-15%), fatigue (2-4%), confusion, headache, insomnia, hypotension, nausea, constipation and urinary frequency.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to baclofen or any component of the formulation.International label, equivalent formulation · Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia

• Abrupt discontinuation can cause anxiety, confusion, hallucinations, psychosis, convulsions (status epilepticus), hyperthermia and rebound spasticity; withdraw gradually over about 1-2 weeks.International label, equivalent formulation · Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia
• Caution in psychiatric disorders, epilepsy/convulsive conditions, peptic ulcer, cerebrovascular disease, respiratory or hepatic insufficiency, porphyria, alcoholism, diabetes and hypertension; suicide-related events and misuse/dependence have been reported.International label, equivalent formulation · Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia
• Encephalopathy (somnolence, confusion, myoclonus, coma) has been reported; discontinue if signs appear.International label, equivalent formulation · Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia

• CNS depressants (other muscle relaxants such as tizanidine, opioids, alcohol)Increased sedation may occur.Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia
• Levodopa/carbidopaMental confusion, hallucinations, headache, nausea, agitation and worsening parkinsonism reported; use with caution.Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia
• Insulin and oral hypoglycaemic agentsBaclofen may increase blood glucose; antidiabetic dosage adjustment may be needed.Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia

• No adequate studies in pregnant women; baclofen crosses the placenta in animals. Use only if the expected benefit outweighs the risk to the foetus.International label, equivalent formulation · Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia
• US label: omphaloceles in rats at about 13 times the maximum human dose; use in pregnancy only if benefit clearly justifies risk.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Data limited to one patient; baclofen was found in quantities so small that infant adverse effects would be unlikely.International label, equivalent formulation · Medicines Information (medsinfo.com.au) / Novartis Pharmaceuticals Australia

• Baclofen: GABA analogue that inhibits monosynaptic and polysynaptic reflexes at the spinal level, possibly by hyperpolarising afferent terminals; supraspinal actions may contribute (US label: precise mechanism not fully known).