سعر بانتروجلوب 40 مجم فيال 2024

Pantroglob pantoprazole 40 mg lyophilised powder in a single vial for intravenous injection/infusion, by Global Napi Pharmaceuticals (Egypt).

• GERD with a history of erosive esophagitis, short-term IV treatment (up to 10 days in adults, 7 days in children >=3 months)Population: Adults and pediatric patients >=3 monthsDailyMed (U.S. National Library of Medicine)
• Pathological hypersecretory conditions including Zollinger-Ellison syndrome (adults)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to any component of the formulation or to any substituted benzimidazole (reactions may include anaphylaxis, angioedema, bronchospasm, acute tubulointerstitial nephritis, urticaria).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant use with rilpivirine-containing products.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Thrombophlebitis has been associated with IV administration; assess and remove the catheter if indicated.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• The US IV product contains edetate disodium (EDTA); consider zinc supplementation in patients prone to zinc deficiency. Whether the Egyptian vial contains EDTA was not verified.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic response does not exclude gastric malignancy.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• RilpivirineContraindicated: reduced rilpivirine exposure and possible loss of virologic response.DailyMed (U.S. National Library of Medicine)
• WarfarinIncreased INR and prothrombin time reported; monitor INR.DailyMed (U.S. National Library of Medicine)
• Methotrexate (high dose)Concomitant use may raise and prolong methotrexate levels; consider temporary PPI withdrawal.DailyMed (U.S. National Library of Medicine)

• US label: available observational data have not shown an association with major malformations or other adverse pregnancy outcomes; animal reproduction studies were reassuring at relevant exposures.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• US label: pantoprazole is present in human milk (limited data); no effects on the breastfed infant have been reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pantoprazole: Binds covalently to the parietal-cell H+/K+-ATPase (proton pump), suppressing the final step of gastric acid production (US label 12.1).