سعر ميجابرازول 20مجم امبول حقن وريدي 2022

Esomeprazole 20 mg for intravenous injection or infusion, single vial.

• Short-term treatment of GERD with erosive esophagitis when oral therapy is not possible or appropriate.Population: Adults and pediatric patients 1 month to 17 yearsDailyMed (U.S. National Library of Medicine)
• Risk reduction of rebleeding of gastric or duodenal ulcers following therapeutic endoscopy for acute bleeding.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Adults (intravenous, 1% or more): headache 11%, flatulence 10%, nausea 6%, abdominal pain 6%, diarrhea 4%, dry mouth 4%, dizziness/vertigo 3%, constipation 3%, injection site reaction 2%, pruritus 1%.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to substituted benzimidazoles or any component (reactions may include anaphylaxis, angioedema, bronchospasm, acute tubulointerstitial nephritis, urticaria).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Co-administration with rilpivirine-containing products.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Symptomatic response does not exclude gastric malignancy; consider further evaluation.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Acute tubulointerstitial nephritis, Clostridioides difficile-associated diarrhea, bone fractures (long-term, high-dose use), severe cutaneous adverse reactions, cutaneous and systemic lupus erythematosus, hypomagnesemia, and fundic gland polyps have been reported with PPIs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Avoid concomitant use with clopidogrel (reduced antiplatelet activity); avoid St John's wort or rifampin (reduced esomeprazole levels); may interfere with chromogranin A tests; may raise methotrexate levels with high-dose methotrexate.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• RilpivirineContraindicated: reduced rilpivirine exposure and loss of virologic response.DailyMed (U.S. National Library of Medicine)
• ClopidogrelReduced active metabolite and antiplatelet activity of clopidogrel; avoid concomitant use.DailyMed (U.S. National Library of Medicine)
• St John's wort, rifampin (CYP2C19/3A4 inducers)Decreased esomeprazole exposure; avoid concomitant use.DailyMed (U.S. National Library of Medicine)

• No adequate and well-controlled studies in pregnant women; epidemiologic data with first-trimester omeprazole (racemate) do not show increased risk of major malformations; animal studies with esomeprazole showed no teratogenicity, but bone changes occurred in rat offspring at high doses.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Limited data suggest omeprazole may be present in human milk; no data on effects on the breastfed infant or milk production; weigh benefits of breastfeeding against maternal need.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Esomeprazole: S-isomer of omeprazole; suppresses gastric acid secretion by inhibiting the H+/K+-ATPase in the gastric parietal cell.