سعر ميرازوديل 40مجم بودر امبول حقن وريدي 2022

Esomeprazole 40 mg powder for intravenous injection, single vial, by Delta Pharma, Egypt.

• GERD with erosive esophagitis when oral therapy is not possible or appropriatePopulation: Adults and pediatric patients 1 month to 17 yearsDailyMed (U.S. National Library of Medicine)
• Risk reduction of rebleeding of gastric or duodenal ulcers following therapeutic endoscopyPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions with intravenous esomeprazole (adults): headache, flatulence, nausea, abdominal pain, injection site reaction, diarrhea, dry mouth, dizziness/vertigo, constipation and pruritus.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to substituted benzimidazoles or any component; co-administration with rilpivirine-containing products.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Symptomatic response does not exclude gastric malignancy. Acute tubulointerstitial nephritis, Clostridioides difficile-associated diarrhea, bone fractures (long-term, high-dose), severe cutaneous adverse reactions, cutaneous and systemic lupus erythematosus, vitamin B12 deficiency (long-term), hypomagnesemia and fundic gland polyps have been reported with PPIs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Use the lowest dose and shortest duration appropriate to the condition. Avoid concomitant St John's wort or rifampin; PPIs may raise chromogranin A levels (stop at least 14 days before CgA testing) and may raise methotrexate levels.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• ClopidogrelEsomeprazole reduces exposure to the active metabolite of clopidogrel (CYP2C19 inhibition); consider an alternative anti-platelet therapy.DailyMed (U.S. National Library of Medicine)
• Rilpivirine; drugs dependent on gastric pH (e.g. ketoconazole, iron salts, erlotinib, mycophenolate mofetil)Rilpivirine is contraindicated; esomeprazole can reduce absorption of drugs that depend on gastric acidity.DailyMed (U.S. National Library of Medicine)
• MethotrexateConcomitant PPI use may elevate and prolong serum methotrexate levels, mainly at high methotrexate doses; consider temporary PPI withdrawal.DailyMed (U.S. National Library of Medicine)

• There are no adequate and well-controlled studies with esomeprazole in pregnant women. Esomeprazole is the S-isomer of omeprazole; available epidemiologic data with omeprazole fail to demonstrate an increased risk of major congenital malformations or other adverse pregnancy outcomes with first-trimester use.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Esomeprazole is likely present in human milk (omeprazole is present in low levels); weigh the benefits of breastfeeding against the mother's clinical need and potential adverse effects on the infant.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

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