سعر سيزرليس اكس ار 500مجم 30 قرص 2024

Seizurless XR 500 mg extended-release tablets: levetiracetam 500 mg, 30 extended-release film-coated tablets, marketed in Egypt by Mash Premiere; an antiepileptic (SV2A ligand).

• Partial-onset seizuresPopulation: 12 years and olderDailyMed (U.S. National Library of Medicine)

• Most common with KEPPRA XR (rates above placebo): irritability and somnolence; others in at least 5% included influenza, nasopharyngitis, dizziness and nausea. Adverse reactions seen with immediate-release levetiracetam may also occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to levetiracetam; reactions have included anaphylaxis and angioedema.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Behavioural abnormalities and psychotic symptoms; suicidal behaviour and ideation (as with all antiepileptic drugs): monitor for mood and behaviour changes.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Somnolence, fatigue and coordination difficulties; patients should not drive or operate machinery until they know how the drug affects them.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Anaphylaxis and angioedema, serious skin reactions (SJS/TEN) and DRESS can occur; discontinue at the first sign of rash unless it is clearly not drug-related.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Prolonged experience in pregnant women has not identified a drug-associated risk of major birth defects or miscarriage. Encourage pregnant patients to enrol in the North American Antiepileptic Drug Pregnancy Registry.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Levetiracetam is excreted in human milk; there are no data on effects on the breastfed infant or on milk production. Weigh the benefits of breastfeeding against the mother's clinical need for the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Levetiracetam: The precise antiepileptic mechanism is unknown; levetiracetam binds the synaptic vesicle protein SV2A, thought to regulate vesicle exocytosis, and SV2A affinity correlated with antiseizure potency in animal models.